Show simple item record

dc.contributor.authorBaird, Denis A.
dc.contributor.authorEvans, Daniel S.
dc.contributor.authorKamanu, Frederick K.
dc.contributor.authorGregory, Jennifer S.
dc.contributor.authorSaunders, Fiona R.
dc.contributor.authorGiuraniuc, Claudiu V.
dc.contributor.authorBarr, Rebecca J.
dc.contributor.authorAspden, Richard M.
dc.contributor.authorJenkins, Deborah
dc.contributor.authorKiel, Douglas P
dc.contributor.authorOrwoll, Eric S.
dc.contributor.authorCummings, Steven R.
dc.contributor.authorLane, Nancy E.
dc.contributor.authorMullin, Benjamin H.
dc.contributor.authorWilliams, Frances MK
dc.contributor.authorRichards, J. Brent
dc.contributor.authorWilson, Scott G
dc.contributor.authorSpector, Tim D.
dc.contributor.authorFaber, Benjamin G.
dc.contributor.authorLawlor, Deborah A.
dc.contributor.authorGrundberg, Elin
dc.contributor.authorOhlsson, Claes
dc.contributor.authorPettersson-Kymmer, Ulrika
dc.contributor.authorCapellini, Terence D.
dc.contributor.authorRichard, Daniel
dc.contributor.authorBeck, Thomas J
dc.contributor.authorEvans, David M.
dc.contributor.authorPaternoster, Lavinia
dc.contributor.authorKarasik, David
dc.contributor.authorTobias, Jonathan H.
dc.date.accessioned2018-11-29T09:50:07Z
dc.date.available2018-11-29T09:50:07Z
dc.date.issued2019-02
dc.identifier.citationBaird , D A , Evans , D S , Kamanu , F K , Gregory , J S , Saunders , F R , Giuraniuc , C V , Barr , R J , Aspden , R M , Jenkins , D , Kiel , D P , Orwoll , E S , Cummings , S R , Lane , N E , Mullin , B H , Williams , F MK , Richards , J B , Wilson , S G , Spector , T D , Faber , B G , Lawlor , D A , Grundberg , E , Ohlsson , C , Pettersson-Kymmer , U , Capellini , T D , Richard , D , Beck , T J , Evans , D M , Paternoster , L , Karasik , D & Tobias , J H 2019 , ' Identification of Novel Loci Associated With Hip Shape : A Meta‐Analysis of Genomewide Association Studies ' Journal of Bone and Mineral Research , vol. 34 , no. 2 , pp. 241-251 . https://doi.org/10.1002/jbmr.3605en
dc.identifier.issn0884-0431
dc.identifier.otherPURE: 139865975
dc.identifier.otherPURE UUID: 066300a4-7c6e-4bb5-8eb7-dfc32b40bdb8
dc.identifier.otherRIS: urn:A02D096E886DAE06206C79F26FF52D1F
dc.identifier.otherPubMed: 30320955
dc.identifier.otherRIS: urn:A02D096E886DAE06206C79F26FF52D1F
dc.identifier.otherScopus: 85057443312
dc.identifier.otherMendeley: 6ac67e55-fa21-34d5-a4b0-76d99a7bca3c
dc.identifier.otherWOS: 000458653600005
dc.identifier.otherORCID: /0000-0001-7130-6777/work/59599902
dc.identifier.urihttp://hdl.handle.net/2164/11532
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85057443312&partnerID=8YFLogxKen
dc.identifier.urihttp://www.mendeley.com/research/identification-novel-loci-associated-hip-shape-metaanalysis-genomewide-association-studiesen
dc.descriptionThis study was funded by Arthritis Research UK project grant 20244, which also provided salary funding for DB and CVG. LP works in the MRC Integrative Epidemiology Unit, a UK MRC‐funded unit (MC_ UU_ 12013/4 & MC_UU_12013/5). ALSPAC: We are extremely grateful to all the families who took part in this study, the midwives for their help in recruiting them, and the whole ALSPAC team, which includes interviewers, computer and laboratory technicians, clerical workers, research scientists, volunteers, managers, receptionists, and nurses. ALSPAC data collection was supported by the Wellcome Trust (grants WT092830M; WT088806; WT102215/2/13/2), UK Medical Research Council (G1001357), and University of Bristol. The UK Medical Research Council and the Wellcome Trust (102215/2/13/2) and the University of Bristol provide core support for ALSPAC. Framingham Heart Study: The Framingham Osteoporosis Study is supported by grants from the National Institute of Arthritis, Musculoskeletal, and Skin Diseases and the National Institute on Aging (R01 AR41398, R01 AR 061162, R01 AR050066, and R01 AR061445). The analyses reflect intellectual input and resource development from the Framingham Heart Study investigators participating in the SNP Health Association Resource project. The Framingham Heart Study of the National Heart, Lung, and Blood Institute of the National Institutes of Health and Boston University School of Medicine were supported by the National Heart, Lung, and Blood Institute's Framingham Heart Study (N01‐HC‐25195) and its contract with Affymetrix, Inc., for genotyping services (N02‐HL‐6‐4278). Analyses reflect intellectual input and resource development from the Framingham Heart Study investigators participating in the SNP Health Association Resource (SHARe) project. A portion of this research was conducted using the Linux Cluster for Genetic Analysis (LinGA‐II) funded by the Robert Dawson Evans Endowment of the Department of Medicine at Boston University School of Medicine and Boston Medical Center. DK was also supported by Israel Science Foundation grant #1283/14. TDC and DR thank Dr Claire Reardon and the entire Harvard University Bauer Core facility for assistance with ATAC‐seq next generation sequencing. This work was funded in part by the Harvard University Milton Fund, NSF (BCS‐1518596), and NIH NIAMS (1R01AR070139‐01A1) to TDC. MrOS: The Osteoporotic Fractures in Men (MrOS) Study is supported by National Institutes of Health funding. The following institutes provide support: the National Institute on Aging (NIA), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Center for Advancing Translational Sciences (NCATS), and NIH Roadmap for Medical Research under the following grant numbers: U01 AG027810, U01 AG042124, U01 AG042139, U01 AG042140, U01 AG042143, U01 AG042145, U01 AG042168, U01 AR066160, and UL1 TR000128. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) provides funding for the MrOS ancillary study “Replication of candidate gene associations and bone strength phenotype in MrOS” under the grant number R01 AR051124. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) provides funding for the MrOS ancillary study “GWAS in MrOS and SOF” under the grant number RC2 AR058973. SOF: The Study of Osteoporotic Fractures (SOF) is supported by National Institutes of Health funding. The National Institute on Aging (NIA) provides support under the following grant numbers: R01 AG005407, R01 AR35582, R01 AR35583, R01 AR35584, R01 AG005394, R01 AG027574, and R01 AG027576. TwinsUK: The study was funded by the Wellcome Trust; European Community's Seventh Framework Programme (FP7/2007‐2013). The study also receives support from the National Institute for Health Research (NIHR)‐funded BioResource, Clinical Research Facility, and Biomedical Research Centre based at Guy's and St Thomas’ NHS Foundation Trust in partnership with King's College London. SNP genotyping was performed by The Wellcome Trust Sanger Institute and National Eye Institute via NIH/CIDR. This study was also supported by the Australian National Health and Medical Research Council (project grants 1048216 and 1127156), the Sir Charles Gairdner Hospital RAC (SGW), and the iVEC/Pawsey Supercomputing Centre (project grants Pawsey0162 and Director2025 [SGW]). The salary of BHM was supported by a Raine Medical Research Foundation Priming Grant. The Umeå Fracture and Osteoporosis Study (UFO) is supported by the Swedish Research Council (K20006‐72X‐20155013), the Swedish Sports Research Council (87/06), the Swedish Society of Medicine, the Kempe‐Foundation (JCK‐1021), and by grants from the Medical Faculty of Umeå Unviersity (ALFVLL:968:22‐2005, ALFVL:‐937‐2006, ALFVLL:223:11‐2007, and ALFVLL:78151‐2009) and from the county council of Västerbotten (Spjutspetsanslag VLL:159:33‐2007). This publication is the work of the authors and does not necessarily reflect the views of any funders. None of the funders had any influence on data collection, analysis, interpretation of the results, or writing of the paper. DB will serve as the guarantor of the paper. Authors’ roles: Study conception and design: DAB, JSG, RMA, LP, DK, and JHT. Data collection: DJ, DPK, ESO, SRC, NEL, BHM, FMKW, JBR, SGW, TDC, BGF, DAL, CO, and UP‐L. Data analysis: DAB, DSE, FKK, JSG, FRS, CVG, RJB, RMA, SGW, EG, TDC, DR, and TB. Data interpretation: JSG, RMA, TDC, DR, DME, LP, DK, and JHT. Drafting manuscript: DAB and JHT. Revising manuscript content: JHT. All authors approved the final version of manuscript. DAB takes responsibility for the integrity of the data analysis.en
dc.format.extent11en
dc.language.isoeng
dc.relation.ispartofJournal of Bone and Mineral Researchen
dc.rights© 2018 The Authors.Journal of Bone and Mineral ResearchPublished by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in anymedium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/en
dc.subjecthip shapeen
dc.subjectosteoarthritisen
dc.subjecthip fracture risken
dc.subjectDXAen
dc.subjectGWASen
dc.subjectHIP FRACTURE RISKen
dc.subjectHIP SHAPEen
dc.subjectOSTEOARTHRITISen
dc.subjectABNORMALITIESen
dc.subjectNONCODING ELEMENTSen
dc.subjectSUSCEPTIBILITY LOCIen
dc.subjectRISKen
dc.subjectINDIAN HEDGEHOGen
dc.subjectPREDICTIONen
dc.subjectFACTOR SOX9en
dc.subjectPARATHYROID-HORMONEen
dc.subjectDIFFERENTIATIONen
dc.subjectR Medicineen
dc.subjectEndocrinology, Diabetes and Metabolismen
dc.subjectOrthopedics and Sports Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMC_ UU_ 12013/4en
dc.subjectMC_UU_12013/5en
dc.subjectArthritis Research UK (ARUK)en
dc.subject20244en
dc.subjectSupplementary data availableen
dc.subject.lccRen
dc.titleIdentification of Novel Loci Associated With Hip Shape : A Meta‐Analysis of Genomewide Association Studiesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen, Medical Educationen
dc.contributor.institutionUniversity of Aberdeen, Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen, Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen, Applied Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1002/jbmr.3605


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record