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Title: Systematic review of economic evaluations and cost analyses of guideline implementation strategies
Authors: Vale, Luke David
Thomas, Ruth Elizabeth
MacLennan, Graeme Stewart
Grimshaw, Jeremy
University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health Sciences
Keywords: Systematic Review
Cost-Benefit Analyses
Practice Guidelines
Cost-effectiveness analysis
physician (or health care professional) behaviour
quality improvement
Issue Date: 2007
Publisher: Springer
Citation: Vale, L., Thomas, R., MacLennan, G., and Grimshaw, J. (2007) Systematic review of economic evaluations and cost analyses of guideline implementation strategies. European Journal of Health Economics, 8, pp.111-121.
Abstract: Objectives To appraise the quality of economic studies undertaken as part of evaluations of guideline implementation strategies; determine their resources use; and recommend methods to improve future studies. Methods Systematic review of economic studies undertaken alongside robust study designs of clinical guideline implementation strategies published (1966-1998). Studies assessed against the BMJ economic evaluations guidelines for each stage of the guideline process (guideline development, implementation and treatment). Results 235 studies were identified, 63 reported some information on cost. Only 3 studies provided evidence that their guideline was effective and efficient. 38 reported the treatment costs only, 12 implementation and treatment costs, 11 implementation costs alone, and two guideline development, implementation and treatment costs. No study gave reasonably complete information on costs. Conclusions Very few satisfactory economic evaluations of guideline implementation strategies have been performed. Current evaluations have numerous methodological defects and rarely consider all relevant costs and benefits. Future evaluations should focus on evaluating the implementation of evidence based guidelines. Keywords: Cost-effectiveness analysis, physician (or health care professional) behaviour, practice guidelines, quality improvement, systematic review.
ISSN: 1618-7598
Rights: The original publication is available at
Appears in Collections:Applied Health Sciences research
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