Now showing items 1-10 of 25
Recruitment to randomised trials : Strategies for Trial Enrolment and Participation Study. The STEPS study
(Gray Publishing, 2007-11)
Objectives: To identify factors associated with good and poor recruitment to multicentre trials. Data sources: Part A: database of trials started in or after 1994 and were due to end before 2003 held by the Medical Research ...
A Pragmatic Randomised, Controlled Trial of Intensive Care follow up programmes in improving Longer-term outcomes from critical illness : the PRACTICAL study
(BioMed Central, 2007-07-23)
Background: A number of intensive care (ICU) patients experience significant problems with physical, psychological, and social functioning for some time after discharge from ICU. These problems have implications not just ...
Protocol for stage 1 of the GAP study (Genetic testing acceptability for Paget's disease of bone):an interview study about genetic testing and preventive treatment
(BMC Health Services Research, 2006-06-08)
Marketing and clinical trials : a case study
(BioMed Central, 2007-11-20)
Background: Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous ...
Randomised trial of glutamine and selenium supplemented parenteral nutrition for critically ill patients
(BioMed Central, 2007-09-20)
Background: Mortality rates in the Intensive Care Unit and subsequent hospital mortality rates in the UK remain high. Infections in Intensive Care are associated with a 2–3 times increased risk of death. It is thought that ...
The effectiveness and cost-effectiveness of minimal access surgery amongst people with gastro-oesophageal reflux disease – a UK collaborative study
(National Institute for Health Research, 2008-09)
*Corresponding author randomised arm of the trial (178 allocated to surgical management,179 allocated to continued, but optimised,medical management) and 453 recruited to the parallel non-randomised preference arm (261 ...
Single imputation methods were inadequate for missing not at random (MNAR) quality of life data
Objective: QoL data were routinely collected in a randomised controlled trial (RCT), which employed a reminder system, retrieving about 50% of data originally missing. The objective was to use this unique feature to ...
Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of the bone) : a questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventative treatment if they were available
(BioMed Central, 2008-05-29)
Background: Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for ...