Browsing by Author "Blazeby, Jane M"

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Challenges in evaluating surgical innovation
(Elsevier, 2009) Ergina, Patrick L; Cook, Jonathan Alistair; Blazeby, Jane M; Clavein, Pierre-Alain; Reeves, Barnaby C; Seiler, Christoph M; Boutron, Isabelle
Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide. In this report, the second of three on surgical innovation and evaluation, we discuss obstacles related to the study design of randomised controlled trials and non-randomised studies assessing surgical interventions. We also describe the issues related to the nature of surgical procedures—for example, their complexity, surgeon-related factors, and the range of outcomes. Although difficult, surgical evaluation is achievable and necessary. Solutions tailored to surgical research and a framework for generating evidence on which to base surgical practice are essential.
Core outcome set for symptomatic uncomplicated gallstone disease
(2022-06-01) Innes, Karen; Hudson, Jemma; Banister, Kathryn; Croal, Bernie; Ramsay, Craig; Ahmed, Irfan; Blazeby, Jane M; Gillies, Katie; CGALL Trial Group; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Other Applied Health Sciences
Development of an online resource for recruitment research in clinical trials to organise and map current literature
(2018-12-01) Kearney, Anna; Harman, Nicola L; Rosala- Hallas, Anna; Beecher, Claire; Blazeby, Jane M; Bower, Peter; Clarke, Mike; Cragg, William; Dune, Sinead; Gardner, Heidi Rebecca; Healy, Patricia; Maguire, Lisa; Mills, Nicola; Rooshenas, Leila; Rowlands, Ceri; Treweek, Shaun; Vellinga, Akke; Williamson, Paula R.; Gamble, Carrol; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences
Further considerations for placebo controls in surgical trials
(2023-06-10) Campbell, Marion K; Beard, David J; Blazeby, Jane M; Cousins, Sian; ASPIRE group; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences
How do pilot and feasibility studies inform randomised placebo-controlled trials in surgery? : A systematic review
(2023-11-20) Cousins, Sian; Gormley, Alexander; Chalmers, Katy; Campbell, Marion K; Beard, David J; Blencowe, Natalie S; Blazeby, Jane M; University of Aberdeen.Aberdeen Centre for Evaluation
Identification and categorisation of relevant outcomes for symptomatic uncomplicated gallstone disease : in depth analysis to inform the development of a core outcome set
(2021-06-24) Cruickshank, Moira; Newlands, Rumana; Blazeby, Jane M; Ahmed, Irfan; Bekheit, Mohamed; Croal, Bernard Lewis; Innes, Karen; Ramsay, Craig; Gillies, Katie; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Education; University of Aberdeen.Institute of Applied Health Sciences
Interventions in randomised controlled trials in surgery : issues to consider during trial design
(2015-09-04) Blencowe, Natalie S; Brown, Julia M; Cook, Jonathan A; Metcalfe, Chris; Morton, Dion G; Nicholl, Jon; Sharples, Linda D; Treweek, Shaun; Blazeby, Jane M; Members of the MRC Hub for Trials Methodology Research Network Workshop; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences
Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones : the C-GALL RCT
(2024-06) Innes, Karen; Ahmed, Irfan; Hudson, Jemma; Hernández, Rodolfo Andrés; Gillies, Katie; Bruce, Rebecca; Bell, Victoria; Avenell, Alison; Blazeby, Jane M; Brazzelli, Miriam; Cotton, Seonaidh; Croal, Bernard; Forrest, Mark; MacLennan, Graeme; Murchie, Peter; Wileman, Samantha; Ramsay, Craig; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Health Economics Research Unit; University of Aberdeen.Institute of Applied Health Sciences
Laparoscopic cholecystectomy versus conservative management for uncomplicated symptomatic gallstones : economic evaluation based on the C-GALL trial
(2025-01) Hernández, Rodolfo Andrés; Ahmed, Irfan; Edwards, Karen; Hudson, Jemma; Gillies, Katie; Bruce, Rebecca; Bell, Victoria; Avenell, Alison; Blazeby, Jane M; Brazzelli, Miriam; Cotton, Seonaidh; Croal, Bernard L.; MacLennan, Graeme; Murchie, Peter; Ramsay, Craig; University of Aberdeen.Health Economics Research Unit; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Centre for Healthcare Randomised Trials (CHaRT); University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences
Patient information leaflets for placebo-controlled surgical trials : a review of current practice and recommendations for developers
(2024-05-22) Cousins, Sian; Huttman, Marc; Blencowe, Natalie S; Tsang, Carmen; Elliott, Daisy; Blazeby, Jane M; Beard, David J; Campbell, Marion; Gillies, Katie; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences
Staff training to improve participant recruitment into surgical randomised controlled trials : A feasibility study within a trial (SWAT) across four host trials simultaneously
(2023-01-01) Parker, A; Arundel, Catherine; Mills, Nicola; Rooshenas, Leila; Jepson, M A; Donovan, J. L.; Blazeby, Jane M; Coleman, Elizabeth; Clark, L; Doherty, Laura; Hewitt, Catherine A; Partha Sarathy , P; Beard, David J; Bower, Peter; Brealey, S; Brocklehurst, P.; Cooper, C; Crofts, J; Culliford, L; Dias, J; Devane, Declan; eldridge, sandra; Emsley, Richard; Galvin, S; Gemperle-Mannion, E; Jayne, D; Metcalfe, A; Montgomery, A; Rangan, A; Sutton, C; Tharmanathan , P; Treweek, Shaun; Torgerson, D; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences