Browsing by Author "Gregory, Jenna"
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Item 40 Years of CSF Toxicity Studies in ALS : What Have We Learnt About ALS Pathophysiology?(2021-03-18) Ng Kee Kwong, Koy Chong; Harbham, Pratap K.; Selvaraj, Bhuvaneish T.; Gregory, Jenna; Pal, Suvankar; Hardingham, Giles E.; Chandran, Siddharthan; Mehta, Arpan R.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Cerebrospinal fluid cytotoxicity in amyotrophic lateral sclerosis : a systematic review of in vitro studies(2020-08-06) Ng Kee Kwong, Koy Chong; Gregory, Jenna; Pal, Suvankar; Chandran, Siddharthan; Mehta, Arpan R.; University of Aberdeen.Medical SciencesItem Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective(2021-10-01) Wong, Charis; Stavrou, Maria; Elliott, Elizabeth; Gregory, Jenna; Leigh, Nigel; Pinto, Ashwin A.; Williams, Timothy L.; Chataway, Jeremy; Swingler, Robert; Parmar, Mahesh K. B.; Stallard, Nigel; Weir, Christopher J; Parker, Richard A; Chaouch, Amina; Hamdalla, Hisham; Ealing, John; Gorrie, George; Morrison, Ian; Duncan, Callum W.; Connelly, Peter; Carod-Artal, Francisco Javier; Davenport, Richard; Reitboeck, Pablo Garcia; Radunovic, Aleksandar; Srinivasan , Venkataramanan; Preston, Jenny; Mehta, Arpan R.; Leighton, Danielle; Glasmacher, Stella; Beswick, Emily; Williamson, Jill; Stenson, Amy; Weaver, Christine; Newton, Judith; Chandran, Siddharthan; Dakin, Rachel; Lyle, Dawn; Pal, Suvankar; Macleod, Malcolm R.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis(2025-01) Rifai, Olivia M.; Waldron, Fergal; Sleibi, Danah; O'shaughnessy, Judi; Leighton, Danielle J.; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Could an Impairment in Local Translation of mRNAs in Glia be Contributing to Pathogenesis in ALS?(2019-05-21) Barton, Samantha Kate; Gregory, Jenna; Chandran, Siddharthan; Turner , Bradley J; University of Aberdeen.Medical SciencesItem Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts(bioRxiv, 2023-01-20) Rifai, Olivia M; O'shaughnessy, Judi; Dando, Owen; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal; Sibley, Christopher R.; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis.(2021-09-21) Gregory, Jenna; Barton, Samantha K.; Selvaraj, Bhuvaneish T.; McDade, Karina; Henstridge, Christopher M.; Spires-Jones, Tara L.; James, Owen G.; Mehta, Arpan R.; Story, David; Burr, Karen; Magnani, Dario; Isaacs, Adrian M.; Smith, Colin; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Dysregulation of AMPA receptor subunit expression in sporadic ALS post‐mortem brain(2020-01) Gregory, Jenna; University of Aberdeen.Medical SciencesItem Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS(2020-02) Gregory, Jenna; McDade, Karina; Bak, Thomas H; Pal, Suvankar; Chandran, Siddharthan; Smith, Colin; Abrahams, Sharon; University of Aberdeen.Medical SciencesItem Genetics of Amyotrophic Lateral Sclerosis(2020-12) Gregory, Jenna; Fagegaltier, Delphine; Phatnani, Hemali; Harms, Matthew B.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical SciencesItem Improved detection of RNA foci in C9orf72 amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction(2020-01) Mehta, Arpan R.; Barton, Samantha K.; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical SciencesItem Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis(2021-02) Mehta, Arpan R.; Gregory, Jenna; Dando, Owen; Carter, Roderick N.; Burr, Karen; Nanda, Jyoti; Story, David; McDade, Karina; Smith, Colin; Morton, Nicholas M.; Mahad, Don J.; Hardingham, Giles E.; Chandran, Siddharthan; Selvaraj, Bhuvaneish T.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis(2022-03) Banerjee, Poulomi; Elliott, Elizabeth; Rifai, Olivia M; O'shaughnessy, Judi; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Probing TDP-43 condensation using an in silico designed aptamer(2022-06-23) Zacco, Elsa; Kantelberg, Owen; Milanetti, Edoardo; Armaos, Alexandros; Panei, Francesco Paolo; Gregory, Jenna; Jeacock, Kiani; Clarke, David J.; Chandran, Siddharthan; Ruocco, Giancarlo; Gustincich, Stefano; Horrocks, Mathew; Pastore, Annalisa; Tartaglia, Gian Gaetano; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Protocol for a systematic review and meta-analysis of experimental models of amyotrophic lateral sclerosis(2016-12) Gregory, Jenna; Waldron, F. M.; Soane, T.; Fulton, L.; Leighton, D.; Chataway, J.; Pal, S.; Chandran, S.; Macleod, M. R.Item pTDP-43 aggregates accumulate in non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis : a case series linking archival surgical biopsies with clinical phenotypic data(2023-01) Pattle, Samuel B.; O'shaughnessy, Judi; Kantelberg, Owen; Rifai, Olivia M; Pate, Judith; Nellany, Kristine; Hays, Nadine; Arends, Mark J.; Horrocks, Mathew; Waldron, Fergal M; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology(2022-01-10) Jiwaji, Zoeb; Tiwari, Sachin S.; Avilés-Reyes, Rolando X.; Hooley, Monique; Hampton, David; Torvell, Megan; Johnson, Delinda A.; McQueen, Jamie; Baxter, Paul; Sabari-Sankar, Kayalvizhi; Qiu, Jing; He, Xin; Fowler, Jill; Febery, James; Gregory, Jenna; Rose, Jamie; Tulloch, Jane; Loan, Jamie; Story, David; McDade, Karina; Smith, Amy M.; Greer, Peta; Ball, Matthew; Kind, Peter C.; Matthews, Paul M.; Smith, Colin; Dando, Owen; Spires-Jones, Tara L.; Johnson, Jeffrey A.; Chandran, Siddharthan; Hardingham, Giles E.Item RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS(2024-06) Spence, Holly; Waldron, Fergal; Saleeb, Rebecca S; Brown, Anna-Leigh; Rifai, Olivia M; Gilodi, Martina; Read, Fiona; Nellany, Kristine; Milne, Gillian; Wilkinson, Debbie; O'shaughnessy, Judi; Pastore, Annalisa; Fratta, Pietro; Shneider, Neil; Tartaglia, Gian Gaetano; Zacco, Elsa; Horrocks, Mathew H; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem A Systematic Approach to Identify Neuroprotective Interventions for Motor Neuron Disease(MedRxiv, 2022-04-22) Wong, Charis; Gregory, Jenna; Liao, Jing; Egan, Kieren; Vesterinen, Hanna M.; Khan, Aimal Ahmad; Anwar, Maarij; Beagan, Caitlin; Brown, Fraser; Cafferkey, John; Cardinali, Alessandra; Chiam, Jane Yi; Chiang, Claire; Collins, Victoria; Dormido, Joyce; Elliott, Elizabeth; Foley, Peter; Foo, Yu Cheng; Fulton-Humble, Lily; Gane, Angus B.; Glasmacher, Stella; Heffernan, Áine; Jayaprakash, Kiran; Jayasuriya, Nimesh; Kaddouri, Amina; Kiernan, Jamie; Langlands, Gavin; Leighton, Danielle; Liu, Jiaming; Lyon, James; Mehta, Arpan R.; Meng, Alyssa; Nguyen, Vivienne; Park, Kyu Hyung; Quigley, Suzanne; Rashid, Yousuf; Salzinger, Andrea; Shiell, Bethany; Singh, Ankur; Soane, Tim; Thompson, Alexandra; Tomala, Olaf; Waldron, Fergal M.; Selvaraj, Bhuvaneish T.; Chataway, Jeremy; Swingler, Robert; Connick, Peter; Pal, Suvankar; Chandran, Siddharthan; Macleod, Malcolm R.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical SciencesItem Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis : a systematic review and meta-analysis(2019-08-06) Mehta, Arpan R.; Walters, Rachel; Waldron, Fergal M.; Pal, Suvankar; Selvaraj, Bhuvaneish T.; Macleod, Malcolm R.; Hardingham, Giles E.; Chandran, Siddharthan; Gregory, Jenna; University of Aberdeen.Medical Sciences