Browsing by Author "Harrington, Charles"
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Item Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease(2018-02-26) Frahm, Silke; Melis, Valeria; Horsley, David; Rickard, Janet; Riedel, Gernot; Fadda, Paula; Scherma, Maria; Harrington, Charles; Wischik, Claude; Theuring, Franz; Schwab, Karima; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Apathy-like behaviour in tau mouse models of Alzheimer’s disease and frontotemporal dementia(2024-01-05) Robinson, Lianne; Dreesen, Eline; Mondesir, Miguel; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Blood Biomarkers from Research Use to Clinical Practice : What Must Be Done? A Report from the EU/US CTAD Task Force(2025-10) Angioni, Davide; Delrieu, J.; Hansson, O.; Fillit, H.; Aisen, P.; Cummings, J.; Sims, J. R.; Braunstein, J. B.; Sabbagh, M.; Bittner, T.; Pontecorvo, M.; Bozeat, S.; Dage, J. L.; Largent, E.; Mattke, S.; Correa, O.; Gutierrez Robledo, L. M.; Baldivieso, V.; Willis, D. R.; Atri, A.; Bateman, R. J.; Ousset, P. J.; Vellas, B.; Weiner, M.; EU/US/CTAD Task Force; Harrington, Charles; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Degeneration of basal and limbic networks is a core feature of behavioural variant frontotemporal dementia(2021-10-21) Vuksanovic, Vesna; Staff, Roger; Morson, Suzannah; Ahearn, Trevor; Bracoud, Luc; Murray, Alison D; Bentham, Peter; Kipps, Christopher M.; Harrington, Charles; Wischik, Claude; University of Aberdeen.Medical Sciences; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Physics; University of Aberdeen.Aberdeen Biomedical Imaging Centre; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection(2021-04-12) Pacheco-Herrero, Mar; Soto-Rojas, Luis O; Harrington, Charles; Flores Martinez, Yazmin M.; Villegas-Rojas, Marcos M; León-Aguilar, Alfredo M.; Martínez-Gómez, Paola A; Campa-Córdoba, B. Berenice; Apátiga-Pérez, Ricardo; Corniel-Taveras, Carolin N.; Dominguez-García, Jesabelle de J.; Blanco-Alvarez, Victor Manuel; Luna-Muñoz, José; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease(2024-10-02) Arastoo, Mohammad; Penny, Lewis Kirk; Lofthouse, Richard Andrew; Abdallah, Aya; Abrahamsson, Anna; Marini, Pietro; Melis, Valeria; Riedel, Gernot; Harrington, Charles; Wischik, Claude; Porter, Andrew; Palliyil, Soumya; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Education; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Microbiology and ImmunityItem Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain(2025-05) Coelho Dos Santos, Renato; Lee, Sophie H; Lofthouse, Richard Andrew; Melis, Valeria; Strachan, Lianne; Leith, Michael; Dreesen, Eline; Armstrong, Paul; Vorley, Thomas; Goatman, Elizabeth; Hull, Claire; Riedel, Gernot; Wischik, Claude; Harrington, Charles; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer’s Disease Brains(2021-04-01) Soto-Rojas, Luis O; Campa-Córdoba, B. Berenice; Harrington, Charles; Salas-Casas, Andrés; Hernandes-Alejandro, Mario; Villanueva-Fierro, Ignacio; Bravo-Muñoz, Marely; Garcés-Ramírez, Linda; De La Cruz-López, Fidel; Ontiveros-Torres, Miguel Angel; Gevorkian, Goar; Pacheco-Herrero, Mar; Luna-Muñoz, José; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy(2024-05-05) Schwab, Karima; Frahm, Silke; Magbagbeolu, Mandy; Horsley, David; Goatman, Elizabeth; Melis, Valeria; Theuring, Franz; Ishaq, Ahtsham; Storey, John M. D.; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.NeuroscienceItem Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease : A meta-analysis 2015-2023(2025-09) Anschuetz, Anne; Schwab, Karima; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine(2024-09) Cranston, Anna; Kraev, Igor; Stewart, Mike G.; Horsley, David; Robinson, Lianne; Dreesen, Eline Stefanie; Armstrong, Paul; Palliyil, Soumya; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Microbiology and Immunity; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.NeuroscienceItem Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia(2025-01) Schwab, Karima; Strachan, Lianne; Anschuetz, Anne; Dreesen, Eline Stefanie; Magbagbeolu, Mandy; Melis, Valeria; Theuring, Franz; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Solubility of α-synuclein species in the L62 mouse model of synucleinopathy(2024-03-14) Schwab, Karima; Magbagbeolu, Mandy; Theuring, Franz; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Medical SciencesItem Systematic gait analysis in alpha-synuclein transgenic line 62 mice using the CatWalk(2026-01-05) Schwab, Karima; Robinson, Lianne; Bray, Jack; Anschuetz, Anne; Mondesir, Miguel; Magri', Monica; Harrington, Charles; Riedel, Gernot; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies(2016-03) Šimić, Goran; Babić Leko, Mirjana; Wray, Selina; Harrington, Charles; Delalle, Ivana; Jovanov-Milošević, Nataša; Bažadona, Danira; Buée, Luc; de Silva, Rohan; Giovanni, Giuseppe Di; Wischik, Claude; Hof, Patrick R.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Tau Protein Phosphorylated at Threonine-231 Is Expressed Abundantly in the Cerebellum in Prion Encephalopathies(2021-05-18) Gómez-López, Víctor Manuel; Viramontes-Pintos, Amparo; Ontiveros-Torres, Miguel Angel; Garcés-Ramírez, Linda; De La Cruz-López, Fidel; Villanueva-Fierro, Ignacio; Bravo-Muñoz, Marely; Harrington, Charles; Martínez-Robles, Sandra; Yescas, Petra; Guadarrama-Ortíz, Parménides; Hernandes-Alejandro, Mario; Montiel-Sosa, José Francisco; Pacheco-Herrero, Mar; Luna-Muñoz, José; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences