University of Aberdeen logo

AURA - Aberdeen University Research Archive

Browsing by Author "Kumar, Vinod"

Filter results by typing the first few letters
Now showing 1 - 10 of 10
  • Thumbnail Image
    Item
    Bowel dysfunction after transposition of intestinal segments into the urinary tract : 8-year prospective cohort study
    (Elsevier, 2007) Somani, Bhaskar K.; Kumar, Vinod; Wong, Susan; Pickard, Robert; Ramsay, Craig R; Nabi, Ghulam; Grant, Adrian Maxwell; N'Dow, James Michael Olu; ABACUS Research Group
    Purpose Bowel function may be disturbed after intestinal segments are transposed into the urinary tract to reconstruct or replace the bladder. In 1997, our group were the first to report major bowel dysfunction in a cohort of such patients: up to 42% of those who were asymptomatic preoperatively describing new bowel symptoms postoperatively including explosive diarrhoea, nocturnal diarrhoea, faecal urgency, faecal incontinence and flatus leakage . We now describe bowel symptoms in this same cohort eight years later (2005). Materials and Methods 116 patients were evaluable. Of the remaining 37 from the original report: 30 had died, five no longer wished to be involved, and two could not be traced. Patients were asked to complete postal questionnaires identical to those used in the first follow-up, assessing the severity of bowel symptoms and quality of life using two validated instruments. Responses were compared with those from the original study. The Nottingham Health Profile quality of life scores were also compared to age and sex matched norms. Results 96 (83%) completed eight-year follow-up questionnaires: 43 after ileal conduit diversion (Group 1), 17 after clam enterocystoplasty for overactive bladder (Group 2), 18 after reconstructed bladder for neurogenic bladder dysfunction (Group 3), and 18 with bladder replacement for non-neurogenic causes (Group 4). High prevalence rates of bowel symptoms persisted with no statistically significant differences between the two time points. Of those with symptoms in 2005, around 50% had reported similar symptoms in 1997. Clam enterocystoplasty patients (Group 2) still reported the highest prevalence (59%) of troublesome diarrhoea with one in two on regular anti-diarrhoeal medication. They also had high rates of faecal incontinence (47%), faecal urgency (41%) and nocturnal bowel movement (18%); with high proportions reporting a moderate or severe adverse effect on work (36%), social life (50%) and sex life (43%). High rates were also reported by neurogenic bladder dysfunction patients, including 50% with troublesome diarrhoea. This symptom was reported by 19% after ileal conduit and by 17% after bladder replacement for non-neurogenic causes. The impact of bowel symptoms on every-day activities and quality of life persisted, remaining most severe after clam enterocystoplasty, with 24% regretting undergoing the procedure because of subsequent bowel symptoms. Conclusions: After more than eight years, operations involving transposition of intestinal segments continue to be associated with high rates of bowel symptoms, which impact on everyday activities. These are particularly troublesome following enterocystoplasty for overactive bladder and bladder reconstruction for neurogenic bladder dysfunction. These risks should influence patient selection and potential patients should be warned prior to surgery.
  • Thumbnail Image
    Item
    Characterizing infection in anti-neutrophil cytoplasmic antibody-associated vasculitis : results from a longitudinal, matched-cohort data linkage study
    (2020-10) Sarica, Shifa H; Dhaun, Neeraj; Sznajd, Jan; Harvie, John; McLaren, John; McGeoch, Lucy; Kumar, Vinod; Amft, Nicole; Erwig, Lars; Marks, Angharad; Black, Corri; Basu, Neil; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Chronic Disease Research Group; University of Aberdeen.Farr Aberdeen; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Health Data Science
  • Thumbnail Image
    Item
    Cost-effectiveness of cognitive behavioural and personalised exercise interventions for reducing fatigue in inflammatory rheumatic diseases
    (2023-12) Chong, Huey Yi; McNamee, Paul; Bachmair, Eva-Maria; Martin, Kathryn; Aucott, Lorna; Dhaun, Neeraj; Dures, Emma; Emsley, Richard; Gray, Stuart Robert; Kidd, Elizabeth; Kumar, Vinod; Lovell, Karina; MacLennan, Graeme; Norrie, John; Paul, Lorna; Packham, Jonathon; Ralston, Stuart H; Siebert, Stefan; Wearden, Alison; Macfarlane, Gary; Basu, Neil; LIFT study group; University of Aberdeen.Health Economics Research Unit; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Epidemiology Group; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Vice Principals
  • Thumbnail Image
    Item
    Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy
    (2015-06-30) Begun, Jakob; Lassen, Kara G; Jijon, Humberto B; Baxt, Leigh A; Goel, Gautam; Heath, Robert J; Ng, Aylwin; Tam, Jenny M; Kuo, Szu-Yu; Villablanca, Eduardo J; Fagbami, Lola; Oosting, Marije; Kumar, Vinod; Schenone, Monica; Carr, Steven A; Joosten, Leo A B; Vyas, Jatin M; Daly, Mark J; Netea, Mihai G; Brown, Gordon D; Wijmenga, Cisca; Xavier, Ramnik J; University of Aberdeen.Applied Medicine
  • No Thumbnail Available
    Item
    Markers for work disability in anti-neutrophil cytoplasmic antibody-associated vasculitis
    (2014-05) Basu, Neil; McClean, Andrew; Harper, Lorraine; Amft, Esther N.; Dhaun, Neeraj; Luqmani, Raashid A.; Little, Mark A.; Jayne, David R. W.; Flossmann, Oliver; McLaren, John; Kumar, Vinod; Erwig, Lars P.; Reid, David M.; Macfarlane, Gary J.; Jones, Gareth T.; University of Aberdeen.Applied Medicine; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Epidemiology Group; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)
  • Thumbnail Image
    Item
    Multimorbidity in Anti-Neutrophil Cytoplasmic Antibody-associated vasculitis : results from a longitudinal, multi-centre data-linkage study
    (2021-04) Sarica, Shifa H; Gallacher, Peter J; Dhaun, Neeraj; Sznajd, Jan; Harvie, John; McLaren, John; McGeoch, Lucy; Kumar, Vinod; Amft, Nicole; Erwig, Lars; Marks, Angharad; Bruno, Laura; Zöllner, York; Black, Corri; Basu, Neil; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Chronic Disease Research Group; University of Aberdeen.Farr Aberdeen; University of Aberdeen.Aberdeen Centre for Health Data Science
  • No Thumbnail Available
    Item
    Predicting functional disability : One year results from the Scottish Early Rheumatoid Arthritis Inception Cohort
    (2016-07) Kronisch, Caroline; McLernon, David J.; Dale, James; Paterson, Caron; Ralston, Stuart H.; Reid, David M.; Tierney, Ann; Harvie, John; McKay, Neil; Wilson, Hilary E.; Munro, Robin; Saunders, Sarah; Richmond, Ruth; Baxter, Derek; McMahon, Mike; Kumar, Vinod; McLaren, John; Siebert, Stefan; McInnes, Iain B.; Porter, Duncan; Macfarlane, Gary J.; Basu, Neil; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Medical Statistics; University of Aberdeen.Applied Medicine; University of Aberdeen.Epidemiology Group; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Institute of Applied Health Sciences
  • Thumbnail Image
    Item
    Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)
    (2019-01) Martin, Kathryn R; Bachmair, Eva-Maria; Aucott, Lorna; Dures, Emma; Emsley, Richard; Gray, Stuart R; Hewlett, Sarah; Kumar, Vinod; Lovell, Karina; Macfarlane, Gary J; MacLennan, Graeme; McNamee, Paul; Norrie, John; Paul, Lorna; Ralston, Stuart; Siebert, Stefan; Wearden, Alison; White, Peter D; Basu, Neil; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Epidemiology Group; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Farr Aberdeen; University of Aberdeen.Health Economics Research Unit
  • No Thumbnail Available
    Item
    Remotely delivered cognitive behavioural and personalised exercise interventions for fatigue severity and impact in inflammatory rheumatic diseases : a multi-centre randomised controlled parallel open-label group trial (LIFT)
    (2022-08-01) Bachmair, Eva-Maria; Martin, Kathryn; Aucott, Lorna; Dhaun, Neeraj; Dures, Emma; Emsley, Richard; Gray, Stuart R.; Kidd, Elizabeth; Kumar, Vinod; Lovell, Karina; MacLennan, Graeme; McNamee, Paul; Norrie, John; Paul, Lorna; Packham, Jonathan; Ralston, Stuart H; Siebert, Stefan; Wearden, Alison; LIFT study group; Macfarlane, Gary; Basu, Neil; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Epidemiology Group; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Health Economics Research Unit; University of Aberdeen.Vice Principals
  • Thumbnail Image
    Item
    The Scottish Early Rheumatoid Arthritis (SERA) Study : an inception cohort and biobank
    (2016-11-09) Dale, James; Paterson, Caron; Tierney, Ann; Ralston, Stuart H; Reid, David M; Basu, Neil; Harvie, John; McKay, Neil D; Saunders, Sarah; Wilson, Hilary; Munro, Robin; Richmond, Ruth; Baxter, Derek; McMahon, Michael; McLaren, John; Kumar, Vinod; Siebert, Stefan; McInnes, Iain; Porter, Duncan; University of Aberdeen.Applied Medicine; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Epidemiology Group; University of Aberdeen.Institute of Applied Health Sciences