Browsing by Author "McEwan, Iain J"
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Item Allosteric Modulators of Steroid Hormone Receptors : Structural Dynamics and Gene Regulation(2012-04-01) Kumar, Raj; McEwan, Iain J; University of Aberdeen.Medical SciencesItem The androgen receptor amino-terminal domain : structure, function and therapeutic potential(2025) Hunter, Irene; Jamieson, Craig; McEwan, Iain J; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medical SciencesItem Eighty Years of Targeting Androgen Receptor Activity in Prostate Cancer : The Fight Goes on(2021-01-29) Estébanez-Perpiñá, Eva; Bevan, Charlotte L; McEwan, Iain J; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medical SciencesItem Functional effects of polymorphisms on glucocorticoid receptor modulation of human anxiogenic substance-P gene promoter activity in primary amygdala neurones(2014-09) Hay, Colin; Shanley, Lynne; Davidson, Scott; Cowie, Philip; Lear, Marissa; McGuffin, Peter; Riedel, Gernot; McEwan, Iain J; MacKenzie, Alasdair; University of Aberdeen.Medical SciencesItem The impact of point mutations in the human androgen receptor : classification of mutations on the basis of transcriptional activity(2012-03-05) Hay, Colin W; McEwan, Iain J; University of Aberdeen.Medical SciencesItem Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the androgen receptor(2025-01) Ahmed, Ikhlas M M; Rofe, Adam; Henry, Martyn C; West, Eric; Jamieson, Craig; McEwan, Iain J; Beveridge, Rebecca; University of Aberdeen.Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Molecular and Cellular Function; University of Aberdeen.Aberdeen Cancer Centre; University of Aberdeen.Institute of Medical SciencesItem Mechanistic insights into steroid hormone-mediated regulation of the androgen receptor gene(2024-08-01) Gillen, Andrew David; Hunter, Irene; Ullner, Ekkehard; McEwan, Iain J; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Physics; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Institute of Medical SciencesItem Negative regulation of the androgen receptor gene through a primate specific androgen response element present in the 5' UTR(2014-10) Hay, Colin W; Watt, Kate; Hunter, Irene; Lavery, Derek N; MacKenzie, Alasdair; McEwan, Iain J; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical SciencesItem Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators(2018-01-02) De Mol, Eva; Szulc, Elzbieta; Di Sanza, Claudio; Martínez-Cristóbal, Paula; Bertoncini, Carlos W; Fenwick, R Bryn; Frigolé-Vivas, Marta; Masín, Marianela; Hunter, Irene; Buzón, Víctor; Brun-Heath, Isabelle; García, Jesús; De Fabritiis, Gianni; Estébanez-Perpiñá, Eva; McEwan, Iain J; Nebreda, Ángel R; Salvatella, Xavier; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical SciencesItem An Sp1 Modulated Regulatory Region Unique to Higher Primates Regulates Human Androgen Receptor Promoter Activity in Prostate Cancer Cells(2015-10-08) Hay, Colin W; Hunter, Irene; MacKenzie, Alasdair; McEwan, Iain J; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical SciencesItem Targeting androgen receptor activation function-1 with EPI to overcome resistance mechanisms in castration-resistant prostate cancer(2016-09-01) Yang, Yu Chi; Banuelos, Carmen Adriana; Mawji, Nasrin R; Wang, Jun; Kato, Minoru; Haile, Simon; McEwan, Iain J; Plymate, Stephen; Sadar, Marianne D; University of Aberdeen.Medical SciencesItem Tissue control of androgen action : The ups and downs of androgen receptor expression(2018-04-15) Hunter, Irene; Hay, Colin W; Esswein, Bianca; Watt, Kate; McEwan, Iain J; University of Aberdeen.Medical Sciences; University of Aberdeen.Biological SciencesItem Topological dynamics of an intrinsically disordered N-terminal domain of the human androgen receptor(2022-06) Sheikhhassani, Vahid; Scalvini, Barbara; Ng, Julian; Heling, Laurens W H J; Ayache, Yosri; Evers, Tom M J; Estébanez-Perpiñá, Eva; McEwan, Iain J; Mashaghi, Alireza; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences