Browsing by Author "Mody, Nimesh"
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Item Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis(2012-02-28) Owen, Carl; Czopek, Alicja; Agouni, Abdelali; Grant, Louise; Judson, Robert; Lees, Emma K; McIlroy, George; Göransson, Olga; Welch, Andy; Bence, Kendra K; Kahn, Barbara B; Neel, Benjamin G; Mody, Nimesh; Delibegovic, Mirela; University of Aberdeen.Biological Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Aberdeen Biomedical Imaging CentreItem Alterations in vitamin A/retinoic acid homeostasis in diet-induced obesity and insulin resistance(2017-11) Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Blood Mononuclear Cell Mitochondrial Respiratory Chain Complex IV Activity Is Decreased in Multiple Sclerosis Patients : Effects of β-Interferon Treatment(2018-02-20) Hargreaves, Iain; Mody, Nimesh; Land, John; Heales, Simon; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia(2018-01) Le Sommer, Samantha; Morrice, Nicola; Pesaresi, Martina; Thompson, Dawn; Vickers, Mark A; Murray, Graeme I; Mody, Nimesh; Neel, Benjamin G; Bence, Kendra K; Wilson, Heather M; Delibegovic, Mirela; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents(2020-08-19) Patruno, Ilaria; Thompson, Dawn; Dall'angelo, Sergio; Windhorst, Albert D.; Vugts, Danielle J.; Poot, Alex J.; Mody, Nimesh; Zanda, Matteo; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Diabetes mellitus in sub-Saharan Africa during the COVID-19 pandemic : a scoping review(2024-07-08) Sseguya, Wenceslaus; Bahendeka, Silver; MacLennan, Sara; Mody, Nimesh; Guntupalli, Aravinda; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Cancer Centre; University of Aberdeen.Academic Urology Unit; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Institute of Medical SciencesItem Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice(2017) Lees, Emma K; Banks, Ruth; Cook, Chelsea; Hill, Sophie; Morrice, Nicola; Grant, Louise; Delibegovic, Mirela; Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice(2015-02) Lees, Emma Katherine; Krol, Elzbieta; Shearer, Kirsty; Mody, Nimesh; Gettys, Thomas W; Delibegovic, Mirela; University of Aberdeen.Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Effects of Liraglutide and Fenretinide treatments on the diabetic phenotype of neuronal human BACE1 knock-in mice(2019-08-01) Dekeryte, Ruta; Hull, Claire; Plucinska, Kaja; Khan, Shakil; Kamli-Salino, Sarah; Mody, Nimesh; Morrice, Nicola; McLaughlin, Chris; Gault, Victor; Platt, Bettina; Delibegovic, Mirela; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice(2017-03-03) Morrice, Nicola; McIlroy, George; Tammireddy, Sheshu R.; Reekie, Jennifer; Shearer, Kirsty D.; Doherty, Mary K; Delibegovic, Mirela; Whitfield, Phillip D.; Mody, Nimesh; University of Aberdeen.Centre for Genome-Enabled Biology and Medicine; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Evaluation of the Epitogen® Lyme Detect IgG ELISA : A Novel Peptide Multiplexing Approach(2024-12-05) Wang, Tiehui; Wang, Alex; Zindrili, Rodanthi; Melis, Elena; Guntupall, Swapna; Brittain-Long, Robin; Delibegovic, Mirela; Secombes, Christopher; Mody, Nimesh; Mavin, Sally; Buks, Ralfs; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological SciencesItem Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR-/- mice(2023-03-09) Thompson, Dawn; Mahmood, Shehroz; Morrice, Nicola; Kamli-Salino, Sarah; Dekeryte, Ruta; Hoffmann, Philip; Doherty, Mary K; Whitfield, Philip D.; Delibegović, Mirela; Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Education; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological SciencesItem Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue(2016-01-15) McIlroy, George; Tammireddy, Seshu R.; Maskrey, Benjamin H.; Grant, Louise; Doherty, Mary K.; Watson, David G.; Delibegovic, Mirela; Whitfield, Philip D.; Mody, Nimesh; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Fenretinide Treatment Prevents Diet-Induced Obesity in Association With Major Alterations in Retinoid Homeostatic Gene Expression in Adipose, Liver and Hypothalamus(2013-03) McIlroy, George D; Delibegovic, Mirela; Owen, Carl; Stoney, Patrick N; Shearer, Kirsty D; McCaffery, Peter J; Mody, Nimesh; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Biological SciencesItem Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction(2014-12-15) Agouni, Abdelali; Tual-Chalot, Simon; Chalopin, Matthieu; Duluc, Lucie; Mody, Nimesh; Martinez, M. Carmen; Andriantsitohaina, Ramaroson; Delibegovic, Mirela; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice(2025-08-01) Mahmood, Shehroz; Morrice, Nicola; Thompson, Dawn; Milanizadeh, Sara; Wilson, Sophie; Whitfield, Philip D; McIlroy, George David; Rochford, Justin; Mody, Nimesh; University of Aberdeen.Medical Education; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress(2011) Agouni, Abdelali; Mody, Nimesh; Owen, Carl; Czopek, Alicja; Zimmer, Derek; Bentirez-Alj, Mohamed; Bence, K. K.; Delibegovic, Mirela; University of Aberdeen.Biological Sciences; University of Aberdeen.Biological SciencesItem The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes(2014-10-01) Mody, Nimesh; McIlroy, George David; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Rowett InstituteItem Methionine restriction improves renal insulin signalling in aged kidneys(2016-07) Grant, Louise; Lees, Emma K.; Forney, Laura A.; Mody, Nimesh; Gettys, Thomas; Brown, Paul A. J.; Wilson, Heather M.; Delibegovic, Mirela; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Applied MedicineItem Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21(2014-10) Lees, Emma K.; Krol, Elzbieta; Grant, Louise; Shearer, Kirsty; Wyse, Cathy; Moncur, Eleanor; Bykowska, Aleksandra S.; Mody, Nimesh; Gettys, Thomas; Delibegovic, Mirela; University of Aberdeen.Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group