Browsing by Author "Steven, John"
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Item Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature(2020-07-21) Leach, Adam; Smyth, Peter; Ferguson, Laura; Steven, John; Greene, Michelle K.; Branco, Cristina M.; McCann, Aidan P.; Porter, Andrew; Barelle, Caroline Jane; Scott, Christopher J.; University of Aberdeen.Medical SciencesItem An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model(2019-03) Ubah, Obinna C.; Steven, John; Porter, Andrew J.; Barelle, Caroline J.; University of Aberdeen.Medical SciencesItem Functionalization of polymeric nanoparticles with targeting VNAR ligands using vinyl sulfone conjugation(2023-05-21) Leach, Adam; Finnegan, Marie; Machado, Mariana S.; Ferguson, Laura; Steven, John; Smyth, Peter; Porter, Andrew; Barelle, Caroline; Themistou, Efrosyni; Scott, Christopher J.; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development(2017-10-23) Steven, John; Müller, Mischa R; Carvalho, Miguel F; Ubah, Obinna C; Kovaleva, Marina; Donohoe, Gerard; Baddeley, Thomas; Cornock, Dawn; Saunders, Kenneth; Porter, Andrew J; Barelle, Caroline Jane; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralising Potency and Multifunctionality, Generated for Therapeutic Development(2017-12-22) Ubah, Obinna C.; Steven, John; Kovaleva, Marina; Ferguson, Laura; Barelle, Charlotte; Porter, Andrew J. R.; Barelle, Caroline J.; University of Aberdeen.Medical SciencesItem Oriented attachment of VNAR proteins, Q2 via site-selective modification, on PLGA–PEG nanoparticles enhances nanoconjugate performance(2019-07-07) Nogueira, Joao C. F.; Greene, Michelle K.; Richards, Daniel A.; Furby, Alexander O.; Steven, John; Porter, Andrew; Barelle, Caroline; Scott, Christopher J.; Chudasama, Vijay; University of Aberdeen.Medical SciencesItem SINGLE DOMAIN BINDING MOLECULE(2013-11-14) University of Aberdeen.Medical Sciences; Barelle, Caroline; Muller, Mischa; Calabro, Valerie; Bikker, Jack; Steven, John; Tchistiakova, Lioudmila; Kovalenko, Oleg V; Olland, AndreaItem Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand(2019-09) Pepple, Kathryn L.; Wilson, Leslie; Van Gelder, Russell N.; Kovaleva, Marina; Ubah, Obinna C.; Steven, John; Barelle, Caroline J.; Porter, Andrew; University of Aberdeen.Medical Sciences