Browsing by Author "Wischik, Claude"
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Item Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease(2018-02-26) Frahm, Silke; Melis, Valeria; Horsley, David; Rickard, Janet; Riedel, Gernot; Fadda, Paula; Scherma, Maria; Harrington, Charles; Wischik, Claude; Theuring, Franz; Schwab, Karima; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Apathy-like behaviour in tau mouse models of Alzheimer’s disease and frontotemporal dementia(2024-01-05) Robinson, Lianne; Dreesen, Eline; Mondesir, Miguel; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration(2020-03-30) Cranston, Anna L; Wysocka, Adrianna; Steczkowska, Marta; Zadrozny, Maciej; Palasz, Ewelina; Harrington, Charles R; Theuring, Franz; Wischik, Claude; Riedel, Gernot; Niewiadomska, Grazyna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Degeneration of basal and limbic networks is a core feature of behavioural variant frontotemporal dementia(2021-10-21) Vuksanovic, Vesna; Staff, Roger; Morson, Suzannah; Ahearn, Trevor; Bracoud, Luc; Murray, Alison D; Bentham, Peter; Kipps, Christopher M.; Harrington, Charles; Wischik, Claude; University of Aberdeen.Medical Sciences; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Physics; University of Aberdeen.Aberdeen Biomedical Imaging Centre; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem The effect of latent confounding processes on the estimation of the strength of causal influences in chain-type networks(2017-09-18) Shiells, Helen Christine; Thiel, Marco; Wischik, Claude; Schelter, Bjoern; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.Physics; University of Aberdeen.Environment and Food Security; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Applied MedicineItem High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease(2024-10-02) Arastoo, Mohammad; Penny, Lewis Kirk; Lofthouse, Richard Andrew; Abdallah, Aya; Abrahamsson, Anna; Marini, Pietro; Melis, Valeria; Riedel, Gernot; Harrington, Charles; Wischik, Claude; Porter, Andrew; Palliyil, Soumya; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Education; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Microbiology and ImmunityItem Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain(2025-05) Coelho Dos Santos, Renato; Lee, Sophie H; Lofthouse, Richard Andrew; Melis, Valeria; Strachan, Lianne; Leith, Michael; Dreesen, Eline; Armstrong, Paul; Vorley, Thomas; Goatman, Elizabeth; Hull, Claire; Riedel, Gernot; Wischik, Claude; Harrington, Charles; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy(2024-05-05) Schwab, Karima; Frahm, Silke; Magbagbeolu, Mandy; Horsley, David; Goatman, Elizabeth; Melis, Valeria; Theuring, Franz; Ishaq, Ahtsham; Storey, John M. D.; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.NeuroscienceItem Obtaining personalized predictions from a randomized controlled trial on Alzheimer’s disease(2025-01-11) Shen, Dennis; Agarwal, Anish; Misra, Vishal; Schelter, Bjoern; Shah, Devavrat; Shiells, Helen; Wischik, Claude; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Physics; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Proteomic and non-proteomic changes of presynaptic proteins in animal models of Alzheimer’s disease : A meta-analysis 2015-2023(2025-09) Anschuetz, Anne; Schwab, Karima; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Rescue of synaptosomal glutamate release defects in tau transgenic mice by the tau aggregation inhibitor hydromethylthionine(2024-09) Cranston, Anna; Kraev, Igor; Stewart, Mike G.; Horsley, David; Robinson, Lianne; Dreesen, Eline Stefanie; Armstrong, Paul; Palliyil, Soumya; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Microbiology and Immunity; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.NeuroscienceItem Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia(2025-01) Schwab, Karima; Strachan, Lianne; Anschuetz, Anne; Dreesen, Eline Stefanie; Magbagbeolu, Mandy; Melis, Valeria; Theuring, Franz; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Solubility of α-synuclein species in the L62 mouse model of synucleinopathy(2024-03-14) Schwab, Karima; Magbagbeolu, Mandy; Theuring, Franz; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Medical SciencesItem Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies(2016-03) Šimić, Goran; Babić Leko, Mirjana; Wray, Selina; Harrington, Charles; Delalle, Ivana; Jovanov-Milošević, Nataša; Bažadona, Danira; Buée, Luc; de Silva, Rohan; Giovanni, Giuseppe Di; Wischik, Claude; Hof, Patrick R.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine