Medical Sciences (Department)
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Item Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline(2017-04-27) Sani, Monica; Lazzari, Paolo; Folini, Marco; Spiga, Marco; Zuco, Valentina; De Cesare, Michelandrea; Manca, Ilaria; Dall'Angelo, Sergio; Frigerio, Massimo; Usai, Igor; Testa, Andrea; Zaffaroni, Nadia; Zanda, Matteo; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem KEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation(2017-05-23) Lazzari, Paolo; Spiga, Marco; Sani, Monica; Zanda, Matteo; Fleming, Ian N; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Education; University of Aberdeen.Aberdeen Biomedical Imaging CentreItem A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives(2016-10-04) Lazzari, Paolo; Distinto, Rita; Manca, Ilaria; Baillie, Gemma; Murineddu , Gabriele; Pira, Marilena; Falzoi, Matteo; Sani, Monica; Morales, Paula; Ross, Ruth; Zanda, Matteo; Jagerovic , Nadine; Pinna, Gerard Aime; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Tricyclic fused pyrazoles with a 'Click' 1,2,3-triazole substituent in position 3 are nanomolar CB1 receptor ligands(2015-03) Zanato, Chiara; Cascio, Maria Grazia; Lazzari, Paolo; Pertwee, Roger; Testa, Andrea; Zanda, Matteo; University of Aberdeen.Medical Sciences; University of Aberdeen.Kosterlitz Centre for Therapeutics; University of Aberdeen.Medical Sciences - Cardiovascular Group