Medical Sciences (Department)
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Item Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia(2018-01) Le Sommer, Samantha; Morrice, Nicola; Pesaresi, Martina; Thompson, Dawn; Vickers, Mark A; Murray, Graeme I; Mody, Nimesh; Neel, Benjamin G; Bence, Kendra K; Wilson, Heather M; Delibegovic, Mirela; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Alterations in vitamin A/retinoic acid homeostasis in diet-induced obesity and insulin resistance(2017-11) Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Pharmacological inhibition of protein tyrosine phosphatase 1B protects against atherosclerotic plaque formation in the LDLR-/- mouse model of atherosclerosis(2017-10-01) Thompson, Dawn; Morrice, Nicola; Grant, Louise; Le Sommer, Samantha; Lees, Emma K; Mody, Nimesh; Wilson, Heather M; Delibegovic, Mirela; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Applied MedicineItem Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice(2017) Lees, Emma K; Banks, Ruth; Cook, Chelsea; Hill, Sophie; Morrice, Nicola; Grant, Louise; Delibegovic, Mirela; Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Methionine restriction improves renal insulin signalling in aged kidneys(2016-07) Grant, Louise; Lees, Emma K.; Forney, Laura A.; Mody, Nimesh; Gettys, Thomas; Brown, Paul A. J.; Wilson, Heather M.; Delibegovic, Mirela; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Applied MedicineItem Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice(2017-03-03) Morrice, Nicola; McIlroy, George; Tammireddy, Sheshu R.; Reekie, Jennifer; Shearer, Kirsty D.; Doherty, Mary K; Delibegovic, Mirela; Whitfield, Phillip D.; Mody, Nimesh; University of Aberdeen.Centre for Genome-Enabled Biology and Medicine; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Neuronal human BACE1 knock-in induces systemic diabetes in mice(2016-07) Plucinska, Kaja; Dekeryte, Ruta; Koss, David; Shearer, Kirsty; Mody, Nimesh; Whitfield, Phillip D.; Doherty, Mary K.; Mingarelli, Marco; Welch, Andy; Riedel, Gernot; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Education; University of Aberdeen.Aberdeen Biomedical Imaging CentreItem Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue(2016-01-15) McIlroy, George; Tammireddy, Seshu R.; Maskrey, Benjamin H.; Grant, Louise; Doherty, Mary K.; Watson, David G.; Delibegovic, Mirela; Whitfield, Philip D.; Mody, Nimesh; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes(2014-10-01) Mody, Nimesh; McIlroy, George David; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Rowett InstituteItem Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis(2012-02-28) Owen, Carl; Czopek, Alicja; Agouni, Abdelali; Grant, Louise; Judson, Robert; Lees, Emma K; McIlroy, George; Göransson, Olga; Welch, Andy; Bence, Kendra K; Kahn, Barbara B; Neel, Benjamin G; Mody, Nimesh; Delibegovic, Mirela; University of Aberdeen.Biological Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Aberdeen Biomedical Imaging Centre