2 - Schools incorporating the Life Sciences and Medicine
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Item Prognostic value of troponins in acute coronary syndrome depends upon patient age(2014-10) Myint, Phyo Kyaw; Kwok, Chun Shing; Bachmann, Max O; Stirling, Susan; Shepstone, Lee; Zaman, M Justin; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Applied MedicineItem British randomised controlled trial of AV and VV optimization ("BRAVO") study : rationale, design, and endpoints(2014-04-03) Whinnett, Zachary I; Sohaib, S M Afzal; Jones, Siana; Kyriacou, Andreas; March, Katherine; Coady, Emma; Mayet, Jamil; Hughes, Alun D; Frenneaux, Michael; Francis, Darrel P; BRAVO Investigators; University of Aberdeen.Applied MedicineItem Utility of B-type natriuretic peptide in predicting medium-term mortality in patients undergoing major non-cardiac surgery(Elsevier, 2007) Cuthbertson, Brian; Amiri, Amir R.; Croal, Bernard L.; Rajagopalan, Sriram; Brittenden, Julie; Hillis, Graham S.; University of Aberdeen, School of Medicine & Dentistry, Division of Applied Health Sciences; University of Aberdeen, School of Medicine & Dentistry, Division of Applied MedicineWe assessed the ability of pre-operative B-type natriuretic peptide (BNP) levels to predict medium-term mortality in patients undergoing major noncardiac surgery. During a median 654 days follow-up 33 patients from a total cohort of 204 patients (16%) died. The optimal cut-off in this cohort, determined using a receiver operating characteristic curve, was >35pg.mL-1. This was associated with a 3.47-fold increase in the hazard of death (p=0.001) and had a sensitivity of 70% and a specificity of 68% for this outcome. These findings extend recent work demonstrating that BNP levels obtained before major noncardiac surgery can be used to predict peri-operative morbidity, and indicate that they also forecast medium-term mortality.