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Item Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts(2023-12-01) Rifai, Olivia M.; O'shaughnessy, Judi; Dando, Owen R.; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal M.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts(bioRxiv, 2023-01-20) Rifai, Olivia M; O'shaughnessy, Judi; Dando, Owen; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal; Sibley, Christopher R.; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS(2022-12) Rifai, Olivia M.; Longden, James; O'Shaughnessy, Judi; Sewell, Michael D.E.; Pate, Judith; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry W.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis(bioRxiv, 2021-12-10) Rifai, Olivia M.; Longden, James; O’Shaughnessy, Judi; Sewell, Michael D.E.; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis(2020-05-18) Gregory, J. M.; Elliott, E.; McDade, K.; Bak, T.; Pal, Suvankar; Chandran, Siddharthan; Abrahams, Sharon; Smith, C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical SciencesItem Improved detection of RNA foci in C9orf72 amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction(2020-01) Mehta, Arpan R.; Barton, Samantha K.; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical SciencesItem Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS(2020-02) Gregory, Jenna; McDade, Karina; Bak, Thomas H; Pal, Suvankar; Chandran, Siddharthan; Smith, Colin; Abrahams, Sharon; University of Aberdeen.Medical SciencesItem NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis(2022-03) Banerjee, Poulomi; Elliott, Elizabeth; Rifai, Olivia M; O'shaughnessy, Judi; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience