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Item A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine(2025-09-01) Al-Hilaly, Youssra K.; Rickard, Janet E.; Simpson, Michael; Storey, John M.D.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Solid-state NMR of paired helical filaments formed by the core tau fragment tau(297-391)(2022-12-08) Al-Hilaly, Youssra K.; Hurt, Connor; Rickard, Janet E.; Harrington, Charles R.; Storey, John M.D.; Wischik, Claude M.; Serpell, Louise C.; Siemer, Ansgar B.; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.ChemistryItem Dityrosine Cross-links are Present in Alzheimer's Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In Vitro(2022-10-15) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Oakley, Sebastian; Burra, Gunasekhar; Khanom, Tahmida; Biasetti, Luca; Mengham, Kurtis; Marshall, Karen; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Structural Identification of Individual Helical Amyloid Filaments by Integration of Cryo-Electron Microscopy-Derived Maps in Comparative Morphometric Atomic Force Microscopy Image Analysis(2022-04-15) Lutter, Liisa; Al-Hilaly, Youssra K.; Serpell, Christopher J.; Tuite, Mick F.; Wischik, Claude M.; Serpell, Louise C.; Xue, Wei Feng; University of Aberdeen.Neuroscience; University of Aberdeen.Applied Medicine; University of Aberdeen.Institute of Medical SciencesItem Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates(2021-03-22) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Burra, Gunasekhar; Rickard, Janet E.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Paired helical filament forming region of tau (297-391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells(2020-08-07) Pollack, Saskia J.; Trigg, Jasmine; Khanom, Tahmida; Biasetti, Luca; Marshall, Karen E.; Al-Hilaly, Youssra K.; Rickard, Janet E.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Other Applied Health Sciences