5 - All research
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Item The effect of dietary weight-loss interventions on the inflammatory markers Interleukin-6 and TNF-alpha in adults with obesity : A systematic review and meta-analysis of randomised controlled clinical trials(2025-07) Bulmer, Cate; Avenell, Alison; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem The effect of weight loss interventions for obesity on fertility and pregnancy outcomes : a systematic review and meta-analysis(2023-05) Boyle, Bonnie R.; Ablett, Andrew D.; Ochi, Christiantus; Hudson, Jemma; Watson, Laura; Rauh, Diayne; Avenell, Alison; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem Fractures in Adults After Weight Loss from Bariatric Surgery and Weight Management Programs for Obesity : Systematic Review and Meta-analysis(2019-04) Ablett, Andrew D.; Boyle, Bonnie R; Avenell, Alison; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem New debate : is it time for infertility weight loss programmes to be couple-based?(2017-12) Best, Damian; Avenell, Alison; Bhattacharya, Siladitya; Stadler, Gertraud; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Grampian Data Safe Haven (DaSH)Item How effective are weight-loss interventions for improving fertility in women and men who are overweight or obese? : A systematic review and meta-analysis of the evidence(2017-11-01) Best, Damian; Avenell, Alison; Bhattacharya, Siladitya; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Grampian Data Safe Haven (DaSH)Item Behavioural Interventions for Severe Obesity Before and/or After Bariatric Surgery : a Systematic Review and Meta-analysis(2016-06) Stewart, Fiona; Avenell, Alison; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem Should weight loss and maintenance programmes be designed differently for men? A systematic review of long-term randomised controlled trials presenting data for men and women : The ROMEO project(2016-01) Robertson, Clare; Avenell, Alison; Boachie, Charles; Stewart, Fiona; Archibald, Daryll; Douglas, Flora; Hoddinott, Pat; van Teijlingen, Edwin; Boyers, Dwayne; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Health Economics Research Unit; University of Aberdeen.Rowett InstituteItem Gaining pounds by losing pounds : HERU Policy Brief(University of Aberdeen, 2015-03) Ryan, Mandy Elaine; Yi, Deokhee; Avenell, Alison; Douglas, Flora Cunningham Gillies; Aucott, Lorna Sharman; Van Teijlingen, Edwin; Vale, Luke D.; University of Aberdeen.Health Economics Research Unit; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Other Applied Health SciencesItem Interventions to achieve long-term weight loss in obese older people(2010-03) Witham, Miles; Avenell, Alison; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Institute of Applied Health SciencesItem Long-term weight loss effects on all cause mortality in overweight/obese populations(Blackwell, 2007-11) Poobalan, Amudha S; Aucott, Lorna S; Smith, W Cairns S; Avenell, Alison; Jung, Roland; Boom, JohnThis systematic review assesses the long-term effectiveness of weight loss on all cause mortality in overweight/obese people. Medline, Embase and Cinahl were searched (1966–2005). Cohort studies and trials on participants with Body Mass Index ¡Ý25 kg/m2, with weight change and mortality with ¡Ý 2 years follow-up were included finally identifying 11 papers based on 8 studies. There may be gender differences in the benefits for all cause mortality. The impact of weight loss in men on mortality was not clear with some studies indicating weight loss to be detrimental, while a recent cohort study showed benefits, if it were a personal decision. Other studies with no gender separation had similarly mixed results. However, one study indicated that overweight/obese women with obesity related illness, who lost weight intentionally within one year, had significantly reduced mortality rates of 19% -25%. In contrast, studies of overweight/obese diabetics irrespective of gender, showed significant benefit of intentional weight loss on mortality in a metaanalysis, HR=0.75(0.67- 0.83). There is some evidence that intentional weight loss has long-term benefits on all cause mortality for women and more so for diabetics. Long-term effects especially for men are not clear and need further investigation.
