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Item PTP1B deficiency in myeloid cells increases susceptibility to Candida albicans systemic infection by modulating antifungal immunity(2025-10) Allen, Bethany; Dambuza, Ivy M.; Berry, Susan; Reid, Delyth Marion; McVey, Sam Morrison; Mesiarikova, Martina; John, Larissa; Davie, Moira; Baker, Christa P; Arthur, J Simon C; Delibegovic, Mirela; Brown, Gordon D.; Wilson, Heather; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Microbiology and ImmunityItem CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment(2019-05) Drummond, Rebecca A.; Swamydas, Muthulekha; Oikonomou, Vasileios; Zhai, Bing; Dambuza, Ivy; Schaefer, Brian C.; Bohrer, Andrea C.; Mayer-Barber, Katrin D.; Lira, Sergio A.; Iwakura, Yoichiro; Filler, Scott G.; Brown, Gordon D.; Hube, Bernhard; Naglik, Julian R.; Hohl, Tobias M.; Lionakis, Michail S.; University of Aberdeen.Applied Medicine; University of Aberdeen.MRC Centre for Medical Mycology; University of Aberdeen.Medical SciencesItem Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity(2020) Gonçalves, Samuel M.; Duarte-Oliveira, Cláudio; Campos, Cláudia F.; Aimanianda, Vishukumar; ter Horst, Rob; Leite, Luis; Mercier, Toine; Pereira, Paulo; Fernández-García, Miguel; Antunes, Daniela; Rodrigues, Cláudia S.; Barbosa-Matos, Catarina; Gaifem, Joana; Mesquita, Inês; Marques, António; Osório, Nuno S.; Torrado, Egídio; Rodrigues, Fernando; Costa, Sandra; Joosten, Leo A.B.; Lagrou, Katrien; Maertens, Johan; Lacerda, João F; Campos Jr, António; Brown, Gordon D.; Brakhage, Axel A; Barbas, Coral; Silvestre, Ricardo; van de Veerdonk, Frank L.; Chamilos, Georgios; Netea, Mihai G.; Latgé, Jean-Paul; Cunha, Cristina; Carvalho, Agostinho; University of Aberdeen.Applied MedicineItem Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion(2019-11-22) Pradhan, Arnab; Avelar, Gabriela M.; Bain, Judith M.; Childers, Delma; Pelletier, Chloe; Larcombe, Daniel E.; Shekhova, Elena; Netea, Mihai G.; Brown, Gordon D.; Erwig, Lars; Gow, Neil A. R.; Brown, Alistair J. P.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.MRC Centre for Medical MycologyItem Memory in Fungal Pathogens Promotes Immune Evasion, Colonisation, and Infection(2019-03) Brown, Alistair J. P.; Gow, Neil A. R.; Warris, Adilia; Brown, Gordon D.; University of Aberdeen.MRC Centre for Medical Mycology; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem The pattern recognition receptors dectin-2, mincle, and FcRγ impact the dynamics of phagocytosis of Candida, Saccharomyces, Malassezia, and Mucor species(2019-08-08) Haider, Mohammed; Dambuza, Ivy; Asamaphan, Patawee; Stappers, Mark; Reid, Delyth; Yamasaki, Sho; Brown, Gordon D.; Gow, Neil A. R.; Erwig, Lars P.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Applied Medicine; University of Aberdeen.MRC Centre for Medical Mycology; University of Aberdeen.Medical SciencesItem The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors(2019-06-26) Thompson, Aiysha; Davies, Luke C.; Laio, Chia-Te; da Fonseca, Diogo M.; Griffiths, James S.; Andrews, Robert; Jones, Adam V.; Clement, Mathew; Brown, Gordon D.; Humphreys, Ian R.; Taylor, Philip R.; Orr, Selinda J.; University of Aberdeen.MRC Centre for Medical Mycology; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Hypoxia Promotes Immune Evasion by Triggering β-glucan Masking on the Candida albicans Cell Surface via Mitochondrial and cAMP-Protein Kinase A Signaling(2018-11-06) Pradhan, Arnab; Avelar, Gabriela M.; Bain, Judith M.; Childers, Delma S; Larcombe, Daniel E.; Netea, Mihai G.; Shekhova, Elena; Munro, Carol A.; Brown, Gordon D.; Erwig, Lars P.; Gow, Neil A. R.; Brown, Alistair J. P.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.MRC Centre for Medical MycologyItem The CLEC12A receptor marks human basophils : Potential implications for minimal residual disease detection in acute myeloid leukemia(2018-05) Toft-Petersen, Marie; Stidsholt Roug, Anne; Plesner, Trine; Ebbesen, Lene; Brown, Gordon D.; Nederby, Line; University of Aberdeen.Applied Medicine; University of Aberdeen.MRC Centre for Medical Mycology; University of Aberdeen.Medical SciencesItem Cytosolic Phospholipase A2α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation(2013-07-25) Suram, Saritha; Silveira, Lori J.; Mahaffey, Spencer; Brown, Gordon D.; Bonventre, Joseph V.; Williams, David L.; Gow, Neil A. R.; Bratton, Donna L.; Murphy, Robert C.; Leslie, Christina C.; University of Aberdeen.Applied Medicine; University of Aberdeen.MRC Centre for Medical Mycology; University of Aberdeen.Medical Sciences