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Item Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS(2022-12) Rifai, Olivia M.; Longden, James; O'Shaughnessy, Judi; Sewell, Michael D.E.; Pate, Judith; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry W.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART) : a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease(2022-07-07) Wong, Charis; Dakin, Rachel S; Williamson, Jill; Newton, Judith; Steven, Michelle; Colville, Shuna; Stavrou, Maria; Gregory, Jenna M; Elliott, Elizabeth; Mehta, Arpan R; Chataway, Jeremy; Swingler, Robert J; Parker, Richard Anthony; Weir, Christopher J; Stallard, Nigel; Parmar, Mahesh K B; Macleod, Malcolm R; Pal, Suvankar; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Spatial transcriptomics identifies spatially dysregulated expression of GRM3 and USP47 in amyotrophic lateral sclerosis(2020-08) Gregory, J. M.; McDade, K.; Livesey, M. R.; Croy, I.; Marion de Proce, S.; Aitman, T.; Chandran, Siddharthan; Smith, C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Natural & Computing SciencesItem A Systematic Approach to Identify Neuroprotective Interventions for Motor Neuron Disease(MedRxiv, 2022-04-22) Wong, Charis; Gregory, Jenna; Liao, Jing; Egan, Kieren; Vesterinen, Hanna M.; Khan, Aimal Ahmad; Anwar, Maarij; Beagan, Caitlin; Brown, Fraser; Cafferkey, John; Cardinali, Alessandra; Chiam, Jane Yi; Chiang, Claire; Collins, Victoria; Dormido, Joyce; Elliott, Elizabeth; Foley, Peter; Foo, Yu Cheng; Fulton-Humble, Lily; Gane, Angus B.; Glasmacher, Stella; Heffernan, Áine; Jayaprakash, Kiran; Jayasuriya, Nimesh; Kaddouri, Amina; Kiernan, Jamie; Langlands, Gavin; Leighton, Danielle; Liu, Jiaming; Lyon, James; Mehta, Arpan R.; Meng, Alyssa; Nguyen, Vivienne; Park, Kyu Hyung; Quigley, Suzanne; Rashid, Yousuf; Salzinger, Andrea; Shiell, Bethany; Singh, Ankur; Soane, Tim; Thompson, Alexandra; Tomala, Olaf; Waldron, Fergal M.; Selvaraj, Bhuvaneish T.; Chataway, Jeremy; Swingler, Robert; Connick, Peter; Pal, Suvankar; Chandran, Siddharthan; Macleod, Malcolm R.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical SciencesItem Probing TDP-43 condensation using an in silico designed aptamer(2022-06-23) Zacco, Elsa; Kantelberg, Owen; Milanetti, Edoardo; Armaos, Alexandros; Panei, Francesco Paolo; Gregory, Jenna; Jeacock, Kiani; Clarke, David J.; Chandran, Siddharthan; Ruocco, Giancarlo; Gustincich, Stefano; Horrocks, Mathew; Pastore, Annalisa; Tartaglia, Gian Gaetano; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis(2022-03) Banerjee, Poulomi; Elliott, Elizabeth; Rifai, Olivia M; O'shaughnessy, Judi; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model(2021) Barton, Samantha K.; Gregory, Jenna; Magnani, Dario; James, Owen G.; Livesey, Matthew R.; Selvaraj, Bhuvaneish T.; James, Owain T.; Perkins, Emma M.; Cleary, Elaine M.; Ausems, C Rosanne M; Carter, Roderick N.; Vasistha, Navneet A.; Zhao, Chen-Ru; Burr, Karen; Story, David; Cardinali, Alessandra; Morton, Nicholas M.; Hardingham, Giles E.; Wyllie, David J. A.; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Clinical trials in amyotrophic lateral sclerosis: a systematic review and perspective(2021-10-01) Wong, Charis; Stavrou, Maria; Elliott, Elizabeth; Gregory, Jenna; Leigh, Nigel; Pinto, Ashwin A.; Williams, Timothy L.; Chataway, Jeremy; Swingler, Robert; Parmar, Mahesh K. B.; Stallard, Nigel; Weir, Christopher J; Parker, Richard A; Chaouch, Amina; Hamdalla, Hisham; Ealing, John; Gorrie, George; Morrison, Ian; Duncan, Callum W.; Connelly, Peter; Carod-Artal, Francisco Javier; Davenport, Richard; Reitboeck, Pablo Garcia; Radunovic, Aleksandar; Srinivasan , Venkataramanan; Preston, Jenny; Mehta, Arpan R.; Leighton, Danielle; Glasmacher, Stella; Beswick, Emily; Williamson, Jill; Stenson, Amy; Weaver, Christine; Newton, Judith; Chandran, Siddharthan; Dakin, Rachel; Lyle, Dawn; Pal, Suvankar; Macleod, Malcolm R.; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience