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Item Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease : Using systematic reviews to inform expert consensus(2023-02) Wong, Charis; Gregory, Jenna M.; Liao, Jing; Egan, Kieren; Vesterinen, Hanna M.; Ahmad Khan, Aimal; Anwar, Maarij; Beagan, Caitlin; Brown, Fraser S.; Cafferkey, John; Cardinali, Alessandra; Chiam, Jane Yi; Chiang, Claire; Collins, Victoria; Dormido, Joyce; Elliott, Elizabeth; Foley, Peter; Foo, Yu Cheng; Fulton-Humble, Lily; Gane, Angus B.; Glasmacher, Stella A.; Heffernan, Áine; Jayaprakash, Kiran; Jayasuriya, Nimesh; Kaddouri, Amina; Kiernan, Jamie; Langlands, Gavin; Leighton, D.; Liu, Jiaming; Lyon, James; Mehta, Arpan R.; Meng, Alyssa; Nguyen, Vivienne; Park, Na Hyun; Quigley, Suzanne; Rashid, Yousuf; Salzinger, Andrea; Shiell, Bethany; Singh, Ankur; Soane, Tim; Thompson, Alexandra; Tomala, Olaf; Waldron, Fergal M.; Selvaraj, Bhuvaneish T.; Chataway, Jeremy; Swingler, Robert; Connick, Peter; Pal, Suvankar; Chandran, Siddharthan; Macleod, Malcolm; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis : a systematic review and meta-analysis(2019-08-06) Mehta, Arpan R.; Walters, Rachel; Waldron, Fergal M.; Pal, Suvankar; Selvaraj, Bhuvaneish T.; Macleod, Malcolm R.; Hardingham, Giles E.; Chandran, Siddharthan; Gregory, Jenna; University of Aberdeen.Medical SciencesItem Improved detection of RNA foci in C9orf72 amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction(2020-01) Mehta, Arpan R.; Barton, Samantha K.; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical SciencesItem Cerebrospinal fluid cytotoxicity in amyotrophic lateral sclerosis : a systematic review of in vitro studies(2020-08-06) Ng Kee Kwong, Koy Chong; Gregory, Jenna; Pal, Suvankar; Chandran, Siddharthan; Mehta, Arpan R.; University of Aberdeen.Medical SciencesItem A Systematic Approach to Identify Neuroprotective Interventions for Motor Neuron Disease(MedRxiv, 2022-04-22) Wong, Charis; Gregory, Jenna; Liao, Jing; Egan, Kieren; Vesterinen, Hanna M.; Khan, Aimal Ahmad; Anwar, Maarij; Beagan, Caitlin; Brown, Fraser; Cafferkey, John; Cardinali, Alessandra; Chiam, Jane Yi; Chiang, Claire; Collins, Victoria; Dormido, Joyce; Elliott, Elizabeth; Foley, Peter; Foo, Yu Cheng; Fulton-Humble, Lily; Gane, Angus B.; Glasmacher, Stella; Heffernan, Áine; Jayaprakash, Kiran; Jayasuriya, Nimesh; Kaddouri, Amina; Kiernan, Jamie; Langlands, Gavin; Leighton, Danielle; Liu, Jiaming; Lyon, James; Mehta, Arpan R.; Meng, Alyssa; Nguyen, Vivienne; Park, Kyu Hyung; Quigley, Suzanne; Rashid, Yousuf; Salzinger, Andrea; Shiell, Bethany; Singh, Ankur; Soane, Tim; Thompson, Alexandra; Tomala, Olaf; Waldron, Fergal M.; Selvaraj, Bhuvaneish T.; Chataway, Jeremy; Swingler, Robert; Connick, Peter; Pal, Suvankar; Chandran, Siddharthan; Macleod, Malcolm R.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical SciencesItem Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology(2022-01-10) Jiwaji, Zoeb; Tiwari, Sachin S.; Avilés-Reyes, Rolando X.; Hooley, Monique; Hampton, David; Torvell, Megan; Johnson, Delinda A.; McQueen, Jamie; Baxter, Paul; Sabari-Sankar, Kayalvizhi; Qiu, Jing; He, Xin; Fowler, Jill; Febery, James; Gregory, Jenna; Rose, Jamie; Tulloch, Jane; Loan, Jamie; Story, David; McDade, Karina; Smith, Amy M.; Greer, Peta; Ball, Matthew; Kind, Peter C.; Matthews, Paul M.; Smith, Colin; Dando, Owen; Spires-Jones, Tara L.; Johnson, Jeffrey A.; Chandran, Siddharthan; Hardingham, Giles E.Item NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis(2022-03) Banerjee, Poulomi; Elliott, Elizabeth; Rifai, Olivia M; O'shaughnessy, Judi; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model(2021) Barton, Samantha K.; Gregory, Jenna; Magnani, Dario; James, Owen G.; Livesey, Matthew R.; Selvaraj, Bhuvaneish T.; James, Owain T.; Perkins, Emma M.; Cleary, Elaine M.; Ausems, C Rosanne M; Carter, Roderick N.; Vasistha, Navneet A.; Zhao, Chen-Ru; Burr, Karen; Story, David; Cardinali, Alessandra; Morton, Nicholas M.; Hardingham, Giles E.; Wyllie, David J. A.; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis(2021-02) Mehta, Arpan R.; Gregory, Jenna; Dando, Owen; Carter, Roderick N.; Burr, Karen; Nanda, Jyoti; Story, David; McDade, Karina; Smith, Colin; Morton, Nicholas M.; Mahad, Don J.; Hardingham, Giles E.; Chandran, Siddharthan; Selvaraj, Bhuvaneish T.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Dysregulation in Subcellular Localization of Myelin Basic Protein mRNA Does Not Result in Altered Myelination in Amyotrophic Lateral Sclerosis.(2021-09-21) Gregory, Jenna; Barton, Samantha K.; Selvaraj, Bhuvaneish T.; McDade, Karina; Henstridge, Christopher M.; Spires-Jones, Tara L.; James, Owen G.; Mehta, Arpan R.; Story, David; Burr, Karen; Magnani, Dario; Isaacs, Adrian M.; Smith, Colin; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience