5 - All research
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Item C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity(2018-01-24) Selvaraj, Bhuvaneish T.; Livesey, Matthew R.; Zhao, Chen; Gregory, Jenna M.; James, Owain T.; Cleary, Elaine M.; Chouhan, Amit K.; Gane, Angus B.; Perkins, Emma M.; Dando, Owen; Lillico, Simon G.; Lee, Youn Bok; Nishimura, Agnes L.; Poreci, Urjana; Thankamony, Sai; Pray, Meryll; Vasistha, Navneet A.; Magnani, Dario; Borooah, Shyamanga; Burr, Karen; Story, David; McCampbell, Alexander; Shaw, Christopher E.; Kind, Peter C.; Aitman, Timothy J.; Whitelaw, C. Bruce A.; Wilmut, Ian; Smith, Colin; Miles, Gareth B.; Hardingham, Giles E.; Wyllie, David J.A.; Chandran, Siddharthan; University of Aberdeen.Medical SciencesItem Therapeutic Targeting of Proteostasis in Amyotrophic Lateral Sclerosis : a Systematic Review and Meta-Analysis of Preclinical Research(2020-05-25) Elliott, Elizabeth; Bailey, Olivia; Waldron, Fergal M.; Hardingham, Giles E.; Chandran, Siddharthan; Gregory, Jenna M.; University of Aberdeen.Medical SciencesItem Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS(2022-12) Rifai, Olivia M.; Longden, James; O'Shaughnessy, Judi; Sewell, Michael D.E.; Pate, Judith; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry W.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease : Using systematic reviews to inform expert consensus(2023-02) Wong, Charis; Gregory, Jenna M.; Liao, Jing; Egan, Kieren; Vesterinen, Hanna M.; Ahmad Khan, Aimal; Anwar, Maarij; Beagan, Caitlin; Brown, Fraser S.; Cafferkey, John; Cardinali, Alessandra; Chiam, Jane Yi; Chiang, Claire; Collins, Victoria; Dormido, Joyce; Elliott, Elizabeth; Foley, Peter; Foo, Yu Cheng; Fulton-Humble, Lily; Gane, Angus B.; Glasmacher, Stella A.; Heffernan, Áine; Jayaprakash, Kiran; Jayasuriya, Nimesh; Kaddouri, Amina; Kiernan, Jamie; Langlands, Gavin; Leighton, D.; Liu, Jiaming; Lyon, James; Mehta, Arpan R.; Meng, Alyssa; Nguyen, Vivienne; Park, Na Hyun; Quigley, Suzanne; Rashid, Yousuf; Salzinger, Andrea; Shiell, Bethany; Singh, Ankur; Soane, Tim; Thompson, Alexandra; Tomala, Olaf; Waldron, Fergal M.; Selvaraj, Bhuvaneish T.; Chataway, Jeremy; Swingler, Robert; Connick, Peter; Pal, Suvankar; Chandran, Siddharthan; Macleod, Malcolm; University of Aberdeen.Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART) : a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease(2022-07-07) Wong, Charis; Dakin, Rachel S; Williamson, Jill; Newton, Judith; Steven, Michelle; Colville, Shuna; Stavrou, Maria; Gregory, Jenna M; Elliott, Elizabeth; Mehta, Arpan R; Chataway, Jeremy; Swingler, Robert J; Parker, Richard Anthony; Weir, Christopher J; Stallard, Nigel; Parmar, Mahesh K B; Macleod, Malcolm R; Pal, Suvankar; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis : a systematic review and meta-analysis(2019-08-06) Mehta, Arpan R.; Walters, Rachel; Waldron, Fergal M.; Pal, Suvankar; Selvaraj, Bhuvaneish T.; Macleod, Malcolm R.; Hardingham, Giles E.; Chandran, Siddharthan; Gregory, Jenna; University of Aberdeen.Medical SciencesItem Spatial transcriptomics identifies spatially dysregulated expression of GRM3 and USP47 in amyotrophic lateral sclerosis(2020-08) Gregory, J. M.; McDade, K.; Livesey, M. R.; Croy, I.; Marion de Proce, S.; Aitman, T.; Chandran, Siddharthan; Smith, C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Natural & Computing SciencesItem Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis(bioRxiv, 2021-12-10) Rifai, Olivia M.; Longden, James; O’Shaughnessy, Judi; Sewell, Michael D.E.; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Neuronal clusterin expression is associated with cognitive protection in amyotrophic lateral sclerosis(2020-05-18) Gregory, J. M.; Elliott, E.; McDade, K.; Bak, T.; Pal, Suvankar; Chandran, Siddharthan; Abrahams, Sharon; Smith, C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical SciencesItem Improved detection of RNA foci in C9orf72 amyotrophic lateral sclerosis post-mortem tissue using BaseScope™ shows a lack of association with cognitive dysfunction(2020-01) Mehta, Arpan R.; Barton, Samantha K.; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical Sciences
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