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Item Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR-/- mice(2023-03-09) Thompson, Dawn; Mahmood, Shehroz; Morrice, Nicola; Kamli-Salino, Sarah; Dekeryte, Ruta; Hoffmann, Philip; Doherty, Mary K; Whitfield, Philip D.; Delibegović, Mirela; Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Education; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological SciencesItem The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice(2021-07-01) Dekeryte, Ruta; Franklin, Zara; Hull, Claire; Croce, Lorenzo; Kamli-Salino, Sarah; Helk, Oliver Walter; Hoffmann, Philip; Yang, Zhixiang; Riedel, Gernot; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Vice Principals; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Phosphoprotein enriched in astrocytes (PEA)-15 is a novel regulator of adipose tissue expansion(2021-03-26) Verschoor, Pola Julia; Greig, Fiona H; Rochford, Justin; Levate', Giovanni; Delibegovic, Mirela; Thompson, Dawn; Leeson-Payne, Alasdair; Dekeryte, Ruta; Banks, Ruth; Ramos, Joe W; Nixon, Graeme; University of Aberdeen.Rowett Institute; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Vice Principals; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Cardiovascular and Diabetes CentreItem NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia(2020-12-01) Hull, Claire; Dekeryte, Ruta; Buchanan, Heather; Kamli-Salino, Sarah; Robertson, Avril; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Neuronal human BACE1 knock-in induces systemic diabetes in mice(2016-07) Plucinska, Kaja; Dekeryte, Ruta; Koss, David; Shearer, Kirsty; Mody, Nimesh; Whitfield, Phillip D.; Doherty, Mary K.; Mingarelli, Marco; Welch, Andy; Riedel, Gernot; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Education; University of Aberdeen.Aberdeen Biomedical Imaging Centre