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Item C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity(2018-01-24) Selvaraj, Bhuvaneish T.; Livesey, Matthew R.; Zhao, Chen; Gregory, Jenna M.; James, Owain T.; Cleary, Elaine M.; Chouhan, Amit K.; Gane, Angus B.; Perkins, Emma M.; Dando, Owen; Lillico, Simon G.; Lee, Youn Bok; Nishimura, Agnes L.; Poreci, Urjana; Thankamony, Sai; Pray, Meryll; Vasistha, Navneet A.; Magnani, Dario; Borooah, Shyamanga; Burr, Karen; Story, David; McCampbell, Alexander; Shaw, Christopher E.; Kind, Peter C.; Aitman, Timothy J.; Whitelaw, C. Bruce A.; Wilmut, Ian; Smith, Colin; Miles, Gareth B.; Hardingham, Giles E.; Wyllie, David J.A.; Chandran, Siddharthan; University of Aberdeen.Medical SciencesItem Therapeutic Targeting of Proteostasis in Amyotrophic Lateral Sclerosis : a Systematic Review and Meta-Analysis of Preclinical Research(2020-05-25) Elliott, Elizabeth; Bailey, Olivia; Waldron, Fergal M.; Hardingham, Giles E.; Chandran, Siddharthan; Gregory, Jenna M.; University of Aberdeen.Medical SciencesItem Targeting mitochondrial dysfunction in amyotrophic lateral sclerosis : a systematic review and meta-analysis(2019-08-06) Mehta, Arpan R.; Walters, Rachel; Waldron, Fergal M.; Pal, Suvankar; Selvaraj, Bhuvaneish T.; Macleod, Malcolm R.; Hardingham, Giles E.; Chandran, Siddharthan; Gregory, Jenna; University of Aberdeen.Medical SciencesItem Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology(2022-01-10) Jiwaji, Zoeb; Tiwari, Sachin S.; Avilés-Reyes, Rolando X.; Hooley, Monique; Hampton, David; Torvell, Megan; Johnson, Delinda A.; McQueen, Jamie; Baxter, Paul; Sabari-Sankar, Kayalvizhi; Qiu, Jing; He, Xin; Fowler, Jill; Febery, James; Gregory, Jenna; Rose, Jamie; Tulloch, Jane; Loan, Jamie; Story, David; McDade, Karina; Smith, Amy M.; Greer, Peta; Ball, Matthew; Kind, Peter C.; Matthews, Paul M.; Smith, Colin; Dando, Owen; Spires-Jones, Tara L.; Johnson, Jeffrey A.; Chandran, Siddharthan; Hardingham, Giles E.Item Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model(2021) Barton, Samantha K.; Gregory, Jenna; Magnani, Dario; James, Owen G.; Livesey, Matthew R.; Selvaraj, Bhuvaneish T.; James, Owain T.; Perkins, Emma M.; Cleary, Elaine M.; Ausems, C Rosanne M; Carter, Roderick N.; Vasistha, Navneet A.; Zhao, Chen-Ru; Burr, Karen; Story, David; Cardinali, Alessandra; Morton, Nicholas M.; Hardingham, Giles E.; Wyllie, David J. A.; Chandran, Siddharthan; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis(2021-02) Mehta, Arpan R.; Gregory, Jenna; Dando, Owen; Carter, Roderick N.; Burr, Karen; Nanda, Jyoti; Story, David; McDade, Karina; Smith, Colin; Morton, Nicholas M.; Mahad, Don J.; Hardingham, Giles E.; Chandran, Siddharthan; Selvaraj, Bhuvaneish T.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem 40 Years of CSF Toxicity Studies in ALS : What Have We Learnt About ALS Pathophysiology?(2021-03-18) Ng Kee Kwong, Koy Chong; Harbham, Pratap K.; Selvaraj, Bhuvaneish T.; Gregory, Jenna; Pal, Suvankar; Hardingham, Giles E.; Chandran, Siddharthan; Mehta, Arpan R.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers(2017) Zanato, Chiara; Pelagalli, Alessia; Marwick, Katie F. M.; Piras, Monica; Dall'Angelo, Sergio; Spinaci, Andrea; Pertwee, Roger G.; Wyllie, David J. A.; Hardingham, Giles E.; Zanda, Matteo; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group