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Item Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies : interference by cholinesterase inhibitors(2024-06-15) Schwab, Karima; Lauer, Dilyara; Magbagbeolu, Mandy; Institute, Mossakowski; Institute, Mossakowski; Institute, Mossakowski; Harrington, Charles R.; Wischik, Claude M.; Niewiadomska, Grażyna; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model : Effects of hydromethylthionine(2022-09-01) Schwab, Karima; Chasapopoulou, Zoi; Frahm, Silke; Magbagbeolu, Mandy; Cranston, Anna; Harrington, Charles R.; Wischik, Claude M.; Theuring, Franz; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Long-term hydromethylthionine treatment is associated with delayed clinical onset and slowing of cerebral atrophy in a pre-symptomatic P301S MAPT mutation carrier(2021-09-28) Bentham, Peter; Staff, Roger T.; Schelter, Bjoern O.; Shiells, Helen; Harrington, Charles R.; Wischik, Claude M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Physics; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Proteomic analysis of hydromethylthionine in the line 66 model of frontotemporal dementia demonstrates actions on tau-dependent and tau-independent networks(2021-08-22) Schwab, Karima; Melis, Valeria; Harrington, Charles R.; Wischik, Claude M.; Magbagbeolu, Mandy; Theuring, Franz; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.NeuroscienceItem Molecular Processing of Tau Protein in Progressive Supranuclear Palsy : Neuronal and Glial Degeneration(2021-02-16) Martínez-Maldonado, Alejandra; Ontiveros-Torres, Miguel Ángel; Harrington, Charles R.; Montiel-Sosa, José Francisco; Prandiz, Raúl García-Tapia; Bocanegra-López, Patricia; Sorsby-Vargas, Andrew Michael; Bravo-Muñoz, Marely; Florán-Garduño, Benjamín; Villanueva-Fierro, Ignacio; Perry, George; Garcés-Ramírez, Linda; De La Cruz-López, Fidel; Martínez-Robles, Sandra; Pacheco-Herrero, Mar; Luna-Muñoz, José; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates(2021-03-22) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Burra, Gunasekhar; Rickard, Janet E.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease(2016-04-08) Lai, Robert Y. K.; Harrington, Charles R.; Wischik, Claude M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine