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Item A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine(2025-09-01) Al-Hilaly, Youssra K.; Rickard, Janet E.; Simpson, Michael; Storey, John M.D.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies : interference by cholinesterase inhibitors(2024-06-15) Schwab, Karima; Lauer, Dilyara; Magbagbeolu, Mandy; Institute, Mossakowski; Institute, Mossakowski; Institute, Mossakowski; Harrington, Charles R.; Wischik, Claude M.; Niewiadomska, Grażyna; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine : A Prospective Study of Phase 3 Clinical Trial Participants(2023-09-06) Arastoo, Mohammad; Mazanetz, Michael P.; Miller, Sonya; Shiells, Helen; Hull, Claire; Robinson, Keith; Storey, John M.D.; Harrington, Charles R.; Wischik, Claude M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Utility of Blood-Based Tau Biomarkers for Mild Cognitive Impairment and Alzheimer’s Disease : Systematic Review and Meta-Analysis(2023-04-18) Zabala-Findlay, Alex; Penny, Lewis K.; Lofthouse, Richard A.; Porter, Andrew J.; Palliyil, Soumya; Harrington, Charles R.; Wischik, Claude M.; Arastoo, Mohammad; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Solid-state NMR of paired helical filaments formed by the core tau fragment tau(297-391)(2022-12-08) Al-Hilaly, Youssra K.; Hurt, Connor; Rickard, Janet E.; Harrington, Charles R.; Storey, John M.D.; Wischik, Claude M.; Serpell, Louise C.; Siemer, Ansgar B.; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.ChemistryItem Dityrosine Cross-links are Present in Alzheimer's Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In Vitro(2022-10-15) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Oakley, Sebastian; Burra, Gunasekhar; Khanom, Tahmida; Biasetti, Luca; Mengham, Kurtis; Marshall, Karen; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Glutamatergic transmission and receptor expression in the synucleinopathy h-α-synL62 mouse model : Effects of hydromethylthionine(2022-09-01) Schwab, Karima; Chasapopoulou, Zoi; Frahm, Silke; Magbagbeolu, Mandy; Cranston, Anna; Harrington, Charles R.; Wischik, Claude M.; Theuring, Franz; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine(2022-04-07) Santos, Renato X.; Melis, Valeria; Goatman, Elizabeth A.; Leith, Michael; Baddeley, Thomas C.; Storey, John M.D.; Riedel, Gernot; Wischik, Claude M.; Harrington, Charles R.; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.NeuroscienceItem Long-term hydromethylthionine treatment is associated with delayed clinical onset and slowing of cerebral atrophy in a pre-symptomatic P301S MAPT mutation carrier(2021-09-28) Bentham, Peter; Staff, Roger T.; Schelter, Bjoern O.; Shiells, Helen; Harrington, Charles R.; Wischik, Claude M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Physics; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Proteomic analysis of hydromethylthionine in the line 66 model of frontotemporal dementia demonstrates actions on tau-dependent and tau-independent networks(2021-08-22) Schwab, Karima; Melis, Valeria; Harrington, Charles R.; Wischik, Claude M.; Magbagbeolu, Mandy; Theuring, Franz; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Neuroscience
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