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Item Dysregulated Alternative Splicing in Breast Cancer Subtypes of RIF1 and Other Transcripts(2025-07-29) Parker, Emma; Akintche, Laura; Pyatnitskaya, Alexandra; Hiraga, Shin-Ichiro; Donaldson, Anne D; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.University of Aberdeen Senate; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Molecular and Cellular FunctionItem The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress(2025-07-01) Dong, Qianqian; Day, Matthew; Saito, Yuichiro; Parker, Emma; Watts, Lotte P; Kanemaki, Masato T; Oliver, Antony W; Pearl, Laurence H; Hiraga, Shin-Ichiro; Donaldson, Anne D; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medical Education; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Molecular and Cellular Function; University of Aberdeen.Aberdeen Cancer CentreItem Checkpoint phosphorylation sites on budding yeast Rif1 protect nascent DNA from degradation by Sgs1-Dna2(2023-12-01) Gali, Vamsi Krishna; Monerawela, Chandre; Laksir, Yassine; Hiraga, Shin-Ichiro; Donaldson, Anne D; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Molecular and Cellular Function; University of Aberdeen.Institute of Medical SciencesItem Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region(2022-04-13) Balasubramanian, Sandhya; Andreani, Matteo; Andrade, Júlia Goncalves; Saha, Tannishtha; Sundaravinayagam, Devakumar; Garzón, Javier; Zhang, Wenzhu; Popp, Oliver; Hiraga, Shin-Ichiro; Rahjouei, Ali; Rosen, Daniel B; Mertins, Philipp; Chait, Brian T; Donaldson, Anne D; Di Virgilio, Michela; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Molecular and Cellular FunctionItem The RIF1-Long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress(2020-11-03) Watts, Lotte P; Natsume, Toyoaki; Saito, Yuichiro; Garzon, Javier; Dong, Qianqian; Boteva, Lora; Gilbert, Nick; Kanemaki, Masato T; Hiraga, Shin-Ichiro; Donaldson, Anne D; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences