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Item Circulating extracellular vesicle-carried PTP1B and PP2A phosphatases as regulators of insulin resistance(2025-01) Ali, Sakina; Vidal-Gómez, Xavier; Piquet, Megan; Vergori, Loiusa; Simard, Gilles; Dubois, Séverine; Ducluzeau, Pierre-Henri; Pomiès, Pascal; Kamli-Salino, Sarah; Delibegovic, Mirela; Henni, Samir; Gagnadoux, Frédéric; Andriantsitohaina, Ramaroson; Martinez, Carmen; Metabol study Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Institute of Medical SciencesItem Myeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism(2023-10-12) Helk, Oliver; Dekeryte, Ruta; Thompson, Dawn; Kamli-Salino, Sarah; Philip, Sam; Wilson, Heather M.; Mody, Nimesh; Delibegovic, Mirela; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Health Data Science; University of Aberdeen.Other Applied Health SciencesItem Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR-/- mice(2023-03-09) Thompson, Dawn; Mahmood, Shehroz; Morrice, Nicola; Kamli-Salino, Sarah; Dekeryte, Ruta; Hoffmann, Philip; Doherty, Mary K; Whitfield, Philip D.; Delibegović, Mirela; Mody, Nimesh; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Cardiometabolic Disease; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Education; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological SciencesItem The BACE1 inhibitor LY2886721 improves diabetic phenotypes of BACE1 knock-in mice(2021-07-01) Dekeryte, Ruta; Franklin, Zara; Hull, Claire; Croce, Lorenzo; Kamli-Salino, Sarah; Helk, Oliver Walter; Hoffmann, Philip; Yang, Zhixiang; Riedel, Gernot; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Vice Principals; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia(2020-12-01) Hull, Claire; Dekeryte, Ruta; Buchanan, Heather; Kamli-Salino, Sarah; Robertson, Avril; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group