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Item Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain(2025-05) Coelho Dos Santos, Renato; Lee, Sophie H; Lofthouse, Richard Andrew; Melis, Valeria; Strachan, Lianne; Leith, Michael; Dreesen, Eline; Armstrong, Paul; Vorley, Thomas; Goatman, Elizabeth; Hull, Claire; Riedel, Gernot; Wischik, Claude; Harrington, Charles; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease(2024-10-02) Arastoo, Mohammad; Penny, Lewis Kirk; Lofthouse, Richard Andrew; Abdallah, Aya; Abrahamsson, Anna; Marini, Pietro; Melis, Valeria; Riedel, Gernot; Harrington, Charles; Wischik, Claude; Porter, Andrew; Palliyil, Soumya; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Education; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Microbiology and ImmunityItem Proteomic analysis of hydromethylthionine in the line 66 model of frontotemporal dementia demonstrates actions on tau-dependent and tau-independent networks(2021-08-22) Schwab, Karima; Melis, Valeria; Harrington, Charles R.; Wischik, Claude M.; Magbagbeolu, Mandy; Theuring, Franz; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.NeuroscienceItem The Neurovascular Unit Dysfunction in Alzheimer's Disease(2021-02-18) Soto-Rojas, Luis O; Pacheco-Herrero, Mar; Martínez-Gómez, Paola A; Campa-Córdoba, B Berenice; Apátiga-Pérez, Ricardo; Villegas-Rojas, Marcos M; Harrington, Charles R; de la Cruz, Fidel; Garcés-Ramírez, Linda; Luna-Muñoz, José; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia(2020-05-19) Shiells, Helen; Schelter, Bjoern O.; Bentham, Peter; Baddeley, Thomas C.; Rubino, Christopher M.; Ganesan, Harish; Hammel, Jeffrey; Vuksanovic, Vesna; Staff, Roger T.; Murray, Alison D.; Bracoud, Luc; Wischik, Damon J.; Riedel, Gernot; Gauthier, Serge; Jia, Jianping; Moebius, Hans J.; Hardlund, Jiri; Kipps, Christopher M.; Kook, Karin; Storey, John M. D.; Harrington, Charles R.; Wischik, Claude M.; University of Aberdeen.Physics; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Chemistry; University of Aberdeen.Applied Medicine; University of Aberdeen.Centre for Health Data Science; University of Aberdeen.Medical Sciences; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Aberdeen Biomedical Imaging Centre