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Item Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain(2025-05) Coelho Dos Santos, Renato; Lee, Sophie H; Lofthouse, Richard Andrew; Melis, Valeria; Strachan, Lianne; Leith, Michael; Dreesen, Eline; Armstrong, Paul; Vorley, Thomas; Goatman, Elizabeth; Hull, Claire; Riedel, Gernot; Wischik, Claude; Harrington, Charles; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts(2023-12-01) Rifai, Olivia M.; O'shaughnessy, Judi; Dando, Owen R.; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal M.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts(bioRxiv, 2023-01-20) Rifai, Olivia M; O'shaughnessy, Judi; Dando, Owen; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal; Sibley, Christopher R.; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS(2022-12) Rifai, Olivia M.; Longden, James; O'Shaughnessy, Judi; Sewell, Michael D.E.; Pate, Judith; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry W.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders(2023-04-26) Kopp, Katherine O.; Greer, Margaret E.; Glotfelty, Elliot J.; Hsueh, Shih-Chang; Tweedie, David; Kim, Dong Seok; Reale, Marcella; Vargesson, Neil; Greig, Nigel H; University of Aberdeen.Medical Sciences; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medical Sciences - Cell, Developmental and Cancer BiologyItem Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis(bioRxiv, 2021-12-10) Rifai, Olivia M.; Longden, James; O’Shaughnessy, Judi; Sewell, Michael D.E.; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection(2021-04-12) Pacheco-Herrero, Mar; Soto-Rojas, Luis O; Harrington, Charles; Flores Martinez, Yazmin M.; Villegas-Rojas, Marcos M; León-Aguilar, Alfredo M.; Martínez-Gómez, Paola A; Campa-Córdoba, B. Berenice; Apátiga-Pérez, Ricardo; Corniel-Taveras, Carolin N.; Dominguez-García, Jesabelle de J.; Blanco-Alvarez, Victor Manuel; Luna-Muñoz, José; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem The therapeutic potential of targeting exchange protein directly activated by cyclic adenosine 3′,5′-monophosphate (Epac) for central nervous system trauma(2021-03) Guijarro Belmar, Alba; Domanski, Dominik Mateusz; Bo, Xuenong; Shewan, Derryck; Huang, Wenlong; University of Aberdeen.Medical Education; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s Disease and Frontotemporal Lobar Degeneration(2020-03-30) Cranston, Anna L; Wysocka, Adrianna; Steczkowska, Marta; Zadrozny, Maciej; Palasz, Ewelina; Harrington, Charles R; Theuring, Franz; Wischik, Claude; Riedel, Gernot; Niewiadomska, Grazyna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Synaptic Loss, ER Stress and Neuro-inflammation Emerge Late in the Lateral Temporal Cortex and Associate with Progressive Tau Pathology in Alzheimer’s Disease(2020-08) Buchanan, Heather; Mackay, Murray; Palmer, Kerri; Tothová, Karolína; Katsur, Miroslava; Platt, Bettina; Koss, David J.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences