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Item A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine(2025-09-01) Al-Hilaly, Youssra K.; Rickard, Janet E.; Simpson, Michael; Storey, John M.D.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Utility of Blood-Based Tau Biomarkers for Mild Cognitive Impairment and Alzheimer’s Disease : Systematic Review and Meta-Analysis(2023-04-18) Zabala-Findlay, Alex; Penny, Lewis K.; Lofthouse, Richard A.; Porter, Andrew J.; Palliyil, Soumya; Harrington, Charles R.; Wischik, Claude M.; Arastoo, Mohammad; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Dityrosine Cross-links are Present in Alzheimer's Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In Vitro(2022-10-15) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Oakley, Sebastian; Burra, Gunasekhar; Khanom, Tahmida; Biasetti, Luca; Mengham, Kurtis; Marshall, Karen; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates(2021-03-22) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Burra, Gunasekhar; Rickard, Janet E.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Cu, Fe, and Zn isotope ratios in murine Alzheimer's disease models suggest specific signatures of amyloidogenesis and tauopathy(2021-01) Solovyev, Nikolay; El-Khatib, Ahmed H.; Costas Rodríguez, Marta; Schwab, Karima; Griffin, Elizabeth; Raab, Andrea; Riedel, Bettina; Theuring, Franz; Vogl, Jochen; Vanhaecke, Frank; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medical SciencesItem Tau Filament Self-Assembly and Structure : Tau as a Therapeutic Target.(2020-11-12) Oakley, Sebastian; Maina, Mahmoud B.; Marshall, Karen E.; Al-Hilaly, Youssra K; Harrington, Charles R; Wischik, Claude M; Serpell, Louise C; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Paired helical filament forming region of tau (297-391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells(2020-08-07) Pollack, Saskia J.; Trigg, Jasmine; Khanom, Tahmida; Biasetti, Luca; Marshall, Karen E.; Al-Hilaly, Youssra K.; Rickard, Janet E.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Other Applied Health SciencesItem Synaptic Loss, ER Stress and Neuro-inflammation Emerge Late in the Lateral Temporal Cortex and Associate with Progressive Tau Pathology in Alzheimer’s Disease(2020-08) Buchanan, Heather; Mackay, Murray; Palmer, Kerri; Tothová, Karolína; Katsur, Miroslava; Platt, Bettina; Koss, David J.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical SciencesItem Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain(2020-03-01) Al-Hilaly, Youssra K; Foster, Bronwen E; Biasetti, Luca; Lutter, Liisa; Pollack, Saskia J; Rickard, Janet E; Storey, John M D; Harrington, Charles R; Xue, Wei-Feng; Wischik, Claude M; Serpell, Louise C; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Medical Sciences