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Item Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia(2025-01) Schwab, Karima; Strachan, Lianne; Anschuetz, Anne; Dreesen, Eline Stefanie; Magbagbeolu, Mandy; Melis, Valeria; Theuring, Franz; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Neuroscience; University of Aberdeen.Institute of Medical SciencesItem Apathy-like behaviour in tau mouse models of Alzheimer’s disease and frontotemporal dementia(2024-01-05) Robinson, Lianne; Dreesen, Eline; Mondesir, Miguel; Harrington, Charles; Wischik, Claude; Riedel, Gernot; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Neuroscience; University of Aberdeen.Applied MedicineItem Apolipoprotein E Loss of Function : Influence on Murine Brain Markers of Physiology and Pathology Aging Brain(2022) Buchanan, Heather; Hull, Claire; Cacho Barraza, Maria; Delibegovic, Mirela; Platt, Bettina; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.NeuroscienceItem Current Progress and Future Directions for Tau-Based Fluid Biomarker Diagnostics in Alzheimer’s Disease(2020-11-26) Arastoo, Mohammad; Lofthouse, Richard; Penny, Lewis; Harrington, Charles R; Porter, Andy; Wischik, Claude M; Palliyil, Soumya; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied MedicineItem Synaptic Loss, ER Stress and Neuro-inflammation Emerge Late in the Lateral Temporal Cortex and Associate with Progressive Tau Pathology in Alzheimer’s Disease(2020-08) Buchanan, Heather; Mackay, Murray; Palmer, Kerri; Tothová, Karolína; Katsur, Miroslava; Platt, Bettina; Koss, David J.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical SciencesItem Distinctive temporal profiles of detergent-soluble and -insoluble tau and Aβ species in human Alzheimer’s disease(2018-11-15) Koss, David J.; Dubini, Marina; Buchanan, Heather; Hull, Claire; Platt, Bettina; University of Aberdeen.Medical Sciences; University of Aberdeen.Biological Sciences; University of Aberdeen.Medicine, Medical Sciences & NutritionItem Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)(2018-10-19) Al-Hilaly, Youssra K.; Pollack, Saskia J.; Rickard, Janet E.; Simpson, Michael; Raulin, Ana-C; Baddeley, Thomas; Schellenberger, Pascale; Storey, John M. D.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Tau-aggregation inhibitor therapy for Alzheimer's disease(2014-04-15) Wischik, Claude M; Harrington, Charles R; Storey, John M D; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry