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Item Distinct neuroinflammatory signatures exist across genetic and sporadic amyotrophic lateral sclerosis cohorts(2023-12-01) Rifai, Olivia M.; O'shaughnessy, Judi; Dando, Owen R.; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal M.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts(bioRxiv, 2023-01-20) Rifai, Olivia M; O'shaughnessy, Judi; Dando, Owen; Munro, Alison F.; Sewell, Michael D.E.; Abrahams, Sharon; Waldron, Fergal; Sibley, Christopher R.; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72-ALS(2022-12) Rifai, Olivia M.; Longden, James; O'Shaughnessy, Judi; Sewell, Michael D.E.; Pate, Judith; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry W.; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Structural brain correlates of childhood trauma with replication across two large, independent community-based samples(2023-01-26) Madden, Rebecca A; Atkinson, Kimberley; Shen, Xueyi; Green, Claire; Hillary, Robert F; Hawkins, Emma; Såge, Emma; Sandu, Anca-Larisa; Waiter, Gordon; McNeil, Christopher; Harris, Mathew; Campbell, Archie; Porteous, David; Macfarlane, Jennifer A; Murray, Alison; Steele, Douglas; Romaniuk, Liana; Lawrie, Stephen M; McIntosh, Andrew M; Whalley, Heather C; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Aberdeen Biomedical Imaging Centre; University of Aberdeen.Applied MedicineItem pTDP-43 aggregates accumulate in non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis : a case series linking archival surgical biopsies with clinical phenotypic data(2023-01) Pattle, Samuel B.; O'shaughnessy, Judi; Kantelberg, Owen; Rifai, Olivia M; Pate, Judith; Nellany, Kristine; Hays, Nadine; Arends, Mark J.; Horrocks, Mathew; Waldron, Fergal M; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.NeuroscienceItem Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis(bioRxiv, 2021-12-10) Rifai, Olivia M.; Longden, James; O’Shaughnessy, Judi; Sewell, Michael D.E.; McDade, Karina; Daniels, Michael J.D.; Abrahams, Sharon; Chandran, Siddharthan; McColl, Barry; Sibley, Christopher R.; Gregory, Jenna M.; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem NLRP3 inflammasome as a key molecular target underlying cognitive resilience in amyotrophic lateral sclerosis(2022-03) Banerjee, Poulomi; Elliott, Elizabeth; Rifai, Olivia M; O'shaughnessy, Judi; McDade, Karina; Abrahams, Sharon; Chandran, Siddharthan; Smith, Colin; Gregory, Jenna; University of Aberdeen.Medical Sciences; University of Aberdeen.NeuroscienceItem Epigenetic prediction of complex traits and death(2018-09-27) McCartney, Daniel L.; Hillary, Robert F.; Stevenson, Anna J.; Ritchie, Stuart J.; Walker, Rosie M.; Zhang, Qian; Morris, Stewart W.; Bermingham, Mairead L.; Campbell, Archie; Murray, Alison D.; Whalley, Heather C.; Gale, Catharine R.; Porteous, David J.; Haley, Chris S.; McRae, Allan F.; Wray, Naomi R.; Visscher, Peter M.; McIntosh, Andrew M.; Evans, Kathryn L.; Deary, Ian J.; Marioni, Riccardo E.; University of Aberdeen.Applied Medicine; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Aberdeen Biomedical Imaging Centre