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Item Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy(2021-01-23) Roumane, Ahlima; Mcilroy, George D; Balci, Arda; Han, Weiping; Delibegović, Mirela; Baldassarre, Massimiliano; Newsholme, Philip; Rochford, Justin J; University of Aberdeen.Rowett Institute; University of Aberdeen.Medical Education; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Medical Sciences; University of Aberdeen.Aberdeen Cardiovascular and Diabetes CentreItem Ablation of Bscl2/Seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy(2020-01-17) Mcilroy, George D; Mitchell, Sharon E; Han, Weiping; Delibegović, Mirela; Rochford, Justin J; University of Aberdeen.Aberdeen Cardiovascular and Diabetes Centre; University of Aberdeen.Rowett Institute; University of Aberdeen.Biological Sciences; University of Aberdeen.Medical Sciences - Cardiovascular Group; University of Aberdeen.Medical SciencesItem Promethin is a Conserved Seipin Partner Protein(2019-03) Castro, Inês G.; Eisenberg-Bord, Michal; Persiani, Elisa; Rochford, Justin J.; Schuldiner, Maya; Bohnert, Maria; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett InstituteItem Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease(2018-04-01) McIlroy, George; Suchacki, Karla; Roelofs, Anke J; Yang, Wulin; Fu, Yanyun; Bai, Bo; Wallace, Robert J; de Bari, Cosimo; Cawthorn, William P; Han, Weiping; Delibegovic, Mirela; Rochford, Justin J.; University of Aberdeen.Rowett Institute; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH); University of Aberdeen.Medical Sciences; University of Aberdeen.Medical Sciences - Cardiovascular GroupItem Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis(2015-03) Talukder, Md. Mesbah Uddin; Sim, M F Michelle; O'Rahilly, Stephen; Edwardson, J Michael; Rochford, Justin J; University of Aberdeen.Rowett InstituteItem Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms(2013-11-01) Sim, M F Michelle; Talukder, M Mesbah Uddin; Dennis, Rowena J; O'Rahilly, Stephen; Edwardson, J Michael; Rochford, Justin J; University of Aberdeen.Rowett Institute