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Item A self-help diet and physical activity intervention with dietetic support for weight management in men treated for prostate cancer : pilot study of the Prostate Cancer Weight Management (PRO-MAN) randomised controlled trial(2019-09-14) Mohamad, H.; Ntessalen, M.; Craig, L. C. A.; Clark, J.; Fielding, S.; N'Dow, J.; Heys, S. D.; McNeill, G.; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Institute of Applied Health Sciences; University of Aberdeen.Academic Urology Unit; University of Aberdeen.Applied MedicineItem Analysis of musculoskeletal and breast tumours by fast field-cycling MRI(2013-10-04) Broche, Lionel; Ashcroft, George Patrick; Boddie, David; Dundas, Sinclair; Gagliardi, Tanja; Heys, Steven Darryll; Lurie, David John; McKenzie, Teena; Miller, Iain; Ross, Peter James; University of Aberdeen.Applied Medicine; University of Aberdeen.Aberdeen Biomedical Imaging Centre; University of Aberdeen.Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH)Item The curious case of an internal pilot in a multicentre randomised trial-time for a rethink?(2016-12-13) Cook, Jonathan Alistair; Beard, David John; Cook, Johanna Rosemary; MacLennan, Graeme Stewart; University of Aberdeen.Aberdeen Centre for Evaluation; University of Aberdeen.Institute of Applied Health SciencesItem A randomised controlled trial of pelvic floor muscle training for stages I and II pelvic organ prolapse(Springer, 2009) Hagen, Suzanne; Stark, Diane; Glazener, Cathryn Margaret Anne; Sinclair, Lesley; Ramsay, IanAbstract Forty-seven women participated in a pilot study for a multi-centre randomized controlled trial of the effectiveness of pelvic floor muscle training (PFMT) for women with prolapse. Women with symptomatic stage I or II prolapse [measured by Pelvic Organ Prolapse Quantification (POP-Q)] were randomized to a 16-week physiotherapy intervention (PFMT and lifestyle advice; n=23) or a control group receiving a lifestyle advice sheet (n=24). Symptom severity and quality of life were measured via postal questionnaires. Blinded POP-Q was performed at baseline and follow-up. Intervention women had significantly greater improvement than controls in prolapse symptoms (mean score decrease 3.5 versus 0.1, p=0.021), were significantly more likely to have an improved prolapse stage (45% versus 0%, p=0.038) and were significantly more likely to say their prolapse was better (63% versus 24%, p=0.012). The data support the feasibility of a substantive trial of PFMT for prolapse. A multi-centre trial is underway.