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Item Gene gain and loss drive the diversification of gig immune genes in teleosts : structural and regulatory insights from Atlantic salmon(2026-01) Manousi, D.; Naseer, S.; Martin, S.A.M; Sandve, S.R.; Saitou, M.; University of Aberdeen.Biological Sciences; University of Aberdeen.Marine Alliance for Science and Technology for Scotland (MASTS); University of Aberdeen.Scottish Fish Immunology Research CentreItem Exploring the roles of conserved context-dependent cis-regulatory elements (ccdCREs) in multicellularity, human health and disease(2025-07-04) McEwan, Andrew Robert; Rattray, Alexander; Hutchings, Greg; Hay, Elizabeth Anne; Murgatroyd, Chris; MacKenzie, Alasdair; University of Aberdeen.Medical Sciences; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Molecular and Cellular Function; University of Aberdeen.Institute of Medical SciencesItem Perspective: Quality Versus Quantity; Is It Important to Assess the Role of Enhancers in Complex Disease from an In Vivo Perspective?(2020-10-23) McEwan, Andrew R; MacKenzie, Alasdair; University of Aberdeen.Medical SciencesItem Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes(2019) Kolb, Andreas F.; Petrie, Linda; Mayer, Claus D.; Pirie, Lynn; Duthie, Susan J.; University of Aberdeen.Rowett InstituteItem A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration(2020-01-31) Strunz, Tobias; Lauwen, Susette; Kiel, Christina; Hollander, Anneke den; Weber, Bernhard H F; International AMD Genomics Consortium (IAMDGC); University of Aberdeen.Medical SciencesItem Regulatory Mechanisms of a Highly Pectinolytic Mutant of Penicillium occitanis and Functional Analysis of a Candidate Gene in the Plant Pathogen Fusarium oxysporum(2017-09-08) Bravo-Ruiz, Gustavo; Sassi, Azza Hadj; Marcet-Houben, Marina; Di Pietro, Antonio; Gargour, Ali; Gabaldon, Toni; Roncero, M. Isabel G.Item Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics(2020-01-01) Hay, Elizabeth A; Cowie, Philip; McEwan, Andrew R; Ross, Ruth; Pertwee, Roger G; MacKenzie, Alasdair; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical SciencesItem Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour(2019-11) Hay, Elizabeth A.; McEwan, Andrew; Wilson, Dana; Barrett, Perry; D'Agostino, Giuseppe; Pertwee, Roger G.; MacKenzie, Alasdair; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Rowett Institute; University of Aberdeen.Institute of Applied Health SciencesItem Exploring the effects of polymorphisms on cis-regulatory signal transduction response(2013-02) MacKenzie, Alasdair; Hing, Benjamin; Davidson, Scott; University of Aberdeen.Medical SciencesItem Functional effects of polymorphisms on glucocorticoid receptor modulation of human anxiogenic substance-P gene promoter activity in primary amygdala neurones(2014-09) Hay, Colin; Shanley, Lynne; Davidson, Scott; Cowie, Philip; Lear, Marissa; McGuffin, Peter; Riedel, Gernot; McEwan, Iain J; MacKenzie, Alasdair; University of Aberdeen.Medical Sciences