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Item A key region of Tau that is able to drive assembly and modulate inhibition by Hydromethylthionine(2025-09-01) Al-Hilaly, Youssra K.; Rickard, Janet E.; Simpson, Michael; Storey, John M.D.; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical SciencesItem Dityrosine Cross-links are Present in Alzheimer's Disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the Stability of the PHF-core Tau (297–391) In Vitro(2022-10-15) Maina, Mahmoud B.; Al-Hilaly, Youssra K.; Oakley, Sebastian; Burra, Gunasekhar; Khanom, Tahmida; Biasetti, Luca; Mengham, Kurtis; Marshall, Karen; Harrington, Charles R.; Wischik, Claude M.; Serpell, Louise C.; University of Aberdeen.Neuroscience; University of Aberdeen.Medical Sciences; University of Aberdeen.Institute of Medical Sciences; University of Aberdeen.Applied MedicineItem Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain(2020-03-01) Al-Hilaly, Youssra K; Foster, Bronwen E; Biasetti, Luca; Lutter, Liisa; Pollack, Saskia J; Rickard, Janet E; Storey, John M D; Harrington, Charles R; Xue, Wei-Feng; Wischik, Claude M; Serpell, Louise C; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Modeling Prion-Like Processing of Tau Protein in Alzheimer's Disease for Pharmaceutical Development(2018-03-13) Wischik, Claude M; Schelter, Björn O; Wischik, Damon J; Storey, John M D; Harrington, Charles R; University of Aberdeen.Applied Medicine; University of Aberdeen.Physics; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking(2017-11-24) Al-Hilaly, Youssra K; Pollack, Saskia J; Vadukul, Devkee; Citossi, Francesca; Rickard, Janet E; Simpson, Michael; Storey, John M D; Harrington, Charles R; Wischik, Claude M; Serpell, Louise C; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Medical Sciences