Chemistry (Department)
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Item Modeling Prion-Like Processing of Tau Protein in Alzheimer's Disease for Pharmaceutical Development(2018-03-13) Wischik, Claude M; Schelter, Björn O; Wischik, Damon J; Storey, John M D; Harrington, Charles R; University of Aberdeen.Applied Medicine; University of Aberdeen.Physics; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy(2018-01-10) Schwab, Karima; Frahm, Silke; Horsley, David; Rickard, Janet E; Melis, Valeria; Goatman, Elizabeth A; Magbagbeolu, Mandy; Douglas, Morag; Leith, Michael G; Baddeley, Thomas C.; Storey, John M D; Riedel, Gernot; Wischik, Claude M; Harrington, Charles R; Theuring, Franz; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.ChemistryItem Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking(2017-11-24) Al-Hilaly, Youssra K; Pollack, Saskia J; Vadukul, Devkee; Citossi, Francesca; Rickard, Janet E; Simpson, Michael; Storey, John M D; Harrington, Charles R; Wischik, Claude M; Serpell, Louise C; University of Aberdeen.Applied Medicine; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease : a randomised, controlled, double-blind, parallel-arm, phase 3 trial(2016-12) Gauthier, Serge; Feldman, Howard H; Schneider, Lon S; Wilcock, Gordon K; Frisoni, Giovanni B; Hardlund, Jiri H; Moebius, Hans J; Bentham, Peter; Kook, Karin A; Wischik, Damon J; Schelter, Bjoern O; Davis, Charles S; Staff, Roger T; Bracoud, Luc; Shamsi, Kohkan; Storey, John M D; Harrington, Charles R; Wischik, Claude M; University of Aberdeen.Medicine, Medical Sciences & Nutrition; University of Aberdeen.Physics; University of Aberdeen.Institute for Complex Systems and Mathematical Biology (ICSMB); University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Applied MedicineItem Electrically tunable laser based on oblique heliconical cholesteric liquid crystal(2016-11-15) Xiang, Jie; Varanytsia, Andrii; Minkowski, Fred; Paterson, Daniel A.; Storey, John M D; Imrie, Corrie T.; Lavrentovich, Oleg D.; Palffy-Muhoray, Peter; University of Aberdeen.Natural & Computing Sciences; University of Aberdeen.Chemistry; University of Aberdeen.EnergyItem Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease(2015-04-24) Harrington, Charles R; Storey, John M D; Clunas, Scott; Harrington, Kathleen A; Horsley, David; Ishaq, Ahtsham; Kemp, Steven J; Larch, Christopher P; Marshall, Colin; Nicoll, Sarah L; Rickard, Janet E; Simpson, Michael; Sinclair, James P; Storey, Lynda J; Wischik, Claude M; University of Aberdeen.Medical Sciences; University of Aberdeen.Chemistry; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Applied MedicineItem Effects of oxidized and reduced forms of methylthioninium in two transgenic mouse tauopathy models(2015-06) Melis, Valeria; Magbagbeolu, Mandy; Rickard, Janet E; Horsley, David; Davidson, Kathleen; Harrington, Kathleen A; Goatman, Keith; Goatman, Elizabeth A; Deiana, Serena; Close, Steve P; Zabke, Claudia; Stamer, Karsten; Dietze, Silke; Schwab, Karima; Storey, John M D; Harrington, Charles R; Wischik, Claude M; Theuring, Franz; Riedel, Gernot; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Epidemiology Group; University of Aberdeen.Chemistry; University of Aberdeen.Medical SciencesItem Tau-aggregation inhibitor therapy for Alzheimer's disease(2014-04-15) Wischik, Claude M; Harrington, Charles R; Storey, John M D; University of Aberdeen.Applied Medicine; University of Aberdeen.Medical Sciences; University of Aberdeen.ChemistryItem Tau Aggregation Inhibitor Therapy : An Exploratory Phase 2 Study in Mild or Moderate Alzheimer's Disease(2015-01-22) Wischik, Claude M; Staff, Roger T; Wischik, Damon J; Bentham, Peter; Murray, Alison D; Storey, John M D; Kook, Karin A; Harrington, Charles R; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Medical Sciences; University of Aberdeen.Applied Medicine; University of Aberdeen.Grampian Data Safe Haven (DaSH); University of Aberdeen.Aberdeen Biomedical Imaging Centre; University of Aberdeen.ChemistryItem Rationale for tau aggregation inhibitor therapy in Alzheimer's disease and other tauopathies(2010) Wischik, Claude M; Wischik, Damon J; Storey, John M D; Harrington, Charles R; Martinez, Ana; University of Aberdeen.Other Applied Health Sciences; University of Aberdeen.Chemistry