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A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT) : study protocol

dc.contributor.authorGreenan, Caroline
dc.contributor.authorMurphy, Lynn
dc.contributor.authorYu, Ly-Mee
dc.contributor.authorKehoe, Patrick G
dc.contributor.authorCoulthard, Elizabeth
dc.contributor.authorBath, Philip
dc.contributor.authorStewart, Robert
dc.contributor.authorJones, Rob
dc.contributor.authorCorbett, Anne
dc.contributor.authorThomas, Alan
dc.contributor.authorConnelly, Peter
dc.contributor.authorArrojo, Frank
dc.contributor.authorCanning, Rachel
dc.contributor.authorWallach, Sylvia
dc.contributor.authorHenderson, Catherine
dc.contributor.authorMcGuinness, Bernadette
dc.contributor.authorO'Sullivan, Mike
dc.contributor.authorHolmes, Clive
dc.contributor.authorKnapp, Martin
dc.contributor.authorBallard, Clive
dc.contributor.authorPassmore, Peter
dc.contributor.authorAFFECT Investigators
dc.contributor.authorSoiza, Roy
dc.date.accessioned2018-03-21T10:05:06Z
dc.date.available2018-03-21T10:05:06Z
dc.date.issued2016-07-18
dc.identifier.citationGreenan , C , Murphy , L , Yu , L-M , Kehoe , P G , Coulthard , E , Bath , P , Stewart , R , Jones , R , Corbett , A , Thomas , A , Connelly , P , Arrojo , F , Canning , R , Wallach , S , Henderson , C , McGuinness , B , O'Sullivan , M , Holmes , C , Knapp , M , Ballard , C , Passmore , P , AFFECT Investigators & Soiza , R 2016 , ' A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT) : study protocol ' , Trials , vol. 17 , 324 . https://doi.org/10.1186/s13063-016-1449-3en
dc.identifier.issn1745-6215
dc.identifier.otherPURE: 117406075
dc.identifier.otherPURE UUID: 66cd80ca-7eb5-4b29-b953-013f9faeeb91
dc.identifier.otherPubMed: 27430267
dc.identifier.otherPubMedCentral: PMC4950108
dc.identifier.otherScopus: 84978791391
dc.identifier.otherORCID: /0000-0002-1397-4272/work/76608927
dc.identifier.urihttp://hdl.handle.net/2164/10204
dc.descriptionThe study is funded by the British Heart Foundation and the Alzheimer’s Society (grant number 184). We wish to acknowledge the support from the staff at the Northern Ireland Clinical Trials Unit; Paul Doherty, Nicola Goodfellow, Roisin Boyle, Mark Wilson, Annmarie Doran, Sam Cassidy and the Belfast Health and Social Care Trust; Margaret McFarland, Fiona Taylor.en
dc.language.isoeng
dc.relation.ispartofTrialsen
dc.rights© 2016 Greenan et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.en
dc.subjectActivities of Daily Livingen
dc.subjectAmlodipineen
dc.subjectBrain Ischemiaen
dc.subjectCalcium Channel Blockersen
dc.subjectClinical Protocolsen
dc.subjectCognitionen
dc.subjectDementia, Vascularen
dc.subjectDouble-Blind Methoden
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMagnetic Resonance Imagingen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNeuropsychological Testsen
dc.subjectQuality of Lifeen
dc.subjectResearch Designen
dc.subjectTime Factorsen
dc.subjectTreatment Outcomeen
dc.subjectUnited Kingdomen
dc.subjectClinical Trial, Phase IIen
dc.subjectJournal Articleen
dc.subjectMulticenter Studyen
dc.subjectRandomized Controlled Trialen
dc.subjectResearch Support, Non-U.S. Gov'ten
dc.subjectR Medicineen
dc.subjectBritish Heart Foundationen
dc.subject.lccRen
dc.titleA randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT) : study protocolen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Health Services Research Uniten
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1186/s13063-016-1449-3
dc.identifier.vol17en


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