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A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

dc.contributor.authorWarren, Anne Y.
dc.contributor.authorMassie, Charlie E.
dc.contributor.authorWatt, Kate
dc.contributor.authorLuko, Katarina
dc.contributor.authorOrafidiya, Folake
dc.contributor.authorSelth, Luke A.
dc.contributor.authorMohammed, Hisham
dc.contributor.authorChohan, Brinder Singh
dc.contributor.authorMenon, Suraj
dc.contributor.authorBaridi, Ajoeb
dc.contributor.authorZhao, Wanfeng
dc.contributor.authorEscriu, Carlos
dc.contributor.authorD'Santos, Clive
dc.contributor.authorTaylor, Chris
dc.contributor.authorQureshi, Arham
dc.contributor.authorZecchini, Vincent R.
dc.contributor.authorShaw, Greg L.
dc.contributor.authorDehm, Scott M.
dc.contributor.authorMills, Ian G.
dc.contributor.authorCarroll, James S.
dc.contributor.authorTilley, Wayne D.
dc.contributor.authorMcEwan, Iain J.
dc.contributor.authorBaniahmad, Aria
dc.contributor.authorNeal, David E.
dc.contributor.authorAsim, Mohammad
dc.date.accessioned2018-09-24T15:10:07Z
dc.date.available2018-09-24T15:10:07Z
dc.date.issued2019-09
dc.identifier.citationWarren , A Y , Massie , C E , Watt , K , Luko , K , Orafidiya , F , Selth , L A , Mohammed , H , Chohan , B S , Menon , S , Baridi , A , Zhao , W , Escriu , C , D'Santos , C , Taylor , C , Qureshi , A , Zecchini , V R , Shaw , G L , Dehm , S M , Mills , I G , Carroll , J S , Tilley , W D , McEwan , I J , Baniahmad , A , Neal , D E & Asim , M 2019 , ' A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer ' , Oncogene , vol. 38 , no. 7 , pp. 1136-1150 . https://doi.org/10.1038/s41388-018-0501-zen
dc.identifier.issn0950-9232
dc.identifier.otherPURE: 137897930
dc.identifier.otherPURE UUID: 87bbf2d9-786c-46d6-80ee-9166a68bec87
dc.identifier.otherScopus: 85053771274
dc.identifier.otherMendeley: 07003e04-de88-3ce2-a344-e96fa777c25b
dc.identifier.otherWOS: 000458624900015
dc.identifier.otherPubMed: 30237440
dc.identifier.urihttp://hdl.handle.net/2164/11167
dc.descriptionWe acknowledge support from the National Cancer Research Institute (National Institute of Health Research (NIHR) collaborative study: “Prostate Cancer: Mechanism of Progression and Treatment (PROMPT)” (grant G0500966/75466). This work was funded by a Cancer Research UK program grant (to DEN) and funding from the US Department of Defense (Prostate Cancer Research Program Transformative Impact Award, grant ID W81XWH-13- 2-0093; WDT, SMD and LAS), National Health and medical Research Council (grant ID 1083961; LAS) and PCFA/Cancer Australia/Movember (grant IDs 1012337 and 1043482; WDT and LAS). The research programs of WDT and LAS are supported by the Movember Foundation and the Prostate Cancer Foundation of Australia through the Movember Revolutionary Team Award. This work was also supported by the National Institutes of Health (NIH) grant R01CA174777 to SMD. FO was supported by a PhD project grant from Prostate Cancer UK (S10-10). LAS and MA were supported by a Young Investigator Award from the Prostate Cancer Foundation of the USA.en
dc.format.extent15
dc.language.isoeng
dc.relation.ispartofOncogeneen
dc.rightsOpen Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectprostate canceren
dc.subjectandrogen receptoren
dc.subjectsignalling kinaseen
dc.subjecttranscriptional regulationen
dc.subjectDOMAINen
dc.subjectORIGINATED PROTEIN-KINASEen
dc.subjectMITOTIC KINASEen
dc.subjectTOPKen
dc.subjectGENEen
dc.subjectANTIANDROGENen
dc.subjectRESISTANCEen
dc.subjectEXPRESSIONen
dc.subjectPBK/TOPKen
dc.subjectABIRATERONEen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectGeneticsen
dc.subjectMolecular Biologyen
dc.subjectCancer Researchen
dc.subjectCancer Research UKen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subjectG0500966/75466en
dc.subjectSupplementary Dataen
dc.subject.lccRC0254en
dc.titleA reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate canceren
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1038/s41388-018-0501-z
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85053771274&partnerID=8YFLogxKen
dc.identifier.urlhttp://www.mendeley.com/research/reciprocal-feedback-between-pdz-binding-kinase-androgen-receptor-drives-prostate-canceren
dc.identifier.vol38en
dc.identifier.iss7en


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