Show simple item record

dc.contributor.authorDambuza, Ivy M
dc.contributor.authorHe, Chang
dc.contributor.authorChoi, Jin Kyeong
dc.contributor.authorYu, Cheng-Rong
dc.contributor.authorWang, Renxi
dc.contributor.authorMattapallil, Mary J
dc.contributor.authorWingfield, Paul T
dc.contributor.authorCaspi, Rachel R
dc.contributor.authorEgwuagu, Charles E
dc.date.accessioned2018-11-20T15:10:07Z
dc.date.available2018-11-20T15:10:07Z
dc.date.issued2017-09-28
dc.identifier.citationDambuza , I M , He , C , Choi , J K , Yu , C-R , Wang , R , Mattapallil , M J , Wingfield , P T , Caspi , R R & Egwuagu , C E 2017 , ' IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease ' , Nature Communications , vol. 8 , 719 . https://doi.org/10.1038/s41467-017-00838-4en
dc.identifier.issn2041-1723
dc.identifier.otherPURE: 140644626
dc.identifier.otherPURE UUID: cd8f5c28-3d67-4852-ad0a-43f2b0e772c0
dc.identifier.otherPubMed: 28959012
dc.identifier.otherPubMedCentral: PMC5620058
dc.identifier.otherScopus: 85030101852
dc.identifier.urihttp://hdl.handle.net/2164/11477
dc.descriptionWe thank Dr. Haohua Qian and Yichao Li (Visual function core, NEI, NIH) for technical assistance with OCT; Phyllis Silver (NEI, NIH) for EAU scoring of the eyes; Rashid Mahdi. M.J.M. for technical assistance with western blot analyses and Rafael Villasmil (NEI FLOW Cytometry Core facility) for assistance with FACS analysis.en
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.rightsOpen Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.en
dc.subjectAnimalsen
dc.subjectAutoimmune Diseases/immunologyen
dc.subjectB-Lymphocytes, Regulatory/metabolismen
dc.subjectCell Proliferationen
dc.subjectImmunosuppressionen
dc.subjectInterleukin-10/metabolismen
dc.subjectInterleukin-12 Receptor beta 2 Subunit/metabolismen
dc.subjectInterleukin-12 Subunit p35/metabolismen
dc.subjectMice, Inbred C57BLen
dc.subjectMice, Knockouten
dc.subjectProtein Multimerizationen
dc.subjectT-Lymphocytes, Regulatory/immunologyen
dc.subjectTh17 Cells/immunologyen
dc.subjectUveitis/immunologyen
dc.subjectQR180 Immunologyen
dc.subject.lccQR180en
dc.titleIL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune diseaseen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1038/s41467-017-00838-4


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record