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Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling

dc.contributor.authorGarzón, Javier
dc.contributor.authorUrsich, Sebastian
dc.contributor.authorLopes, Massimo
dc.contributor.authorHiraga, Shin-ichiro
dc.contributor.authorDonaldson, Anne D.
dc.date.accessioned2019-06-04T13:10:07Z
dc.date.available2019-06-04T13:10:07Z
dc.date.issued2019-05-28
dc.identifier.citationGarzón , J , Ursich , S , Lopes , M , Hiraga , S & Donaldson , A D 2019 , ' Human RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stalling ' , Cell Reports , vol. 27 , no. 9 , pp. 2558-2566.e4 . https://doi.org/10.1016/j.celrep.2019.05.002en
dc.identifier.issn2211-1247
dc.identifier.otherPURE: 143579474
dc.identifier.otherPURE UUID: dc633333-7918-4e6b-b94f-828527d3c880
dc.identifier.otherScopus: 85065894680
dc.identifier.otherMendeley: 47fff1b0-1abd-3951-bf3f-13b4197cf584
dc.identifier.otherPubMed: 31141682
dc.identifier.otherORCID: /0000-0002-8722-3869/work/58936356
dc.identifier.otherORCID: /0000-0002-5093-8385/work/58936620
dc.identifier.otherWOS: 000469216500005
dc.identifier.urihttp://hdl.handle.net/2164/12356
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85065894680&partnerID=8YFLogxKen
dc.identifier.urihttp://www.mendeley.com/research/human-rif1protein-phosphatase-1-prevents-degradation-breakage-nascent-dna-replication-stallingen
dc.descriptionWe thank the Microscopy Core and Proteomics Core Facilities at Aberdeen University for assistance and analysis. pCMV-Flag-WRN plasmid was kindly gifted by Pietro Pichierri. NSC-105808 from Grzegorz Ira lab was gifted by Alessandro Vindigni. We thank all the members of our lab and Takashi Kubota for helpful discussions. This research was supported by Cancer Research UK Programme Award A19059 to ADD and SH.en
dc.format.extent14
dc.language.isoeng
dc.relation.ispartofCell Reportsen
dc.rightsUnder a Creative Commons license https://creativecommons.org/licenses/by/4.0/en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectDNA Replicationen
dc.subjectFork Protectionen
dc.subjectReplication stressen
dc.subjectGenome Integrityen
dc.subjectRIF1-PP1en
dc.subjectDNA2en
dc.subjectWRNen
dc.subjectR Medicine (General)en
dc.subjectBiochemistry, Genetics and Molecular Biology(all)en
dc.subjectCancer Research UKen
dc.subjectA19059en
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleHuman RIF1-Protein Phosphatase 1 Prevents Degradation and Breakage of Nascent DNA on Replication Stallingen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1016/j.celrep.2019.05.002
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85065894680&partnerID=8YFLogxKen
dc.identifier.urlhttp://www.mendeley.com/research/human-rif1protein-phosphatase-1-prevents-degradation-breakage-nascent-dna-replication-stallingen
dc.identifier.vol27en
dc.identifier.iss9en


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