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dc.contributor.authorAhmed, Suaad
dc.contributor.authorBusetti, Alessandro
dc.contributor.authorFotiadou, Parthena
dc.contributor.authorVincy Jose, Nisha
dc.contributor.authorReid, Sarah
dc.contributor.authorGeorgieva, Marieta
dc.contributor.authorBrown, Samantha
dc.contributor.authorDunbar, Hayley
dc.contributor.authorBeurket-Ascencio, Gloria
dc.contributor.authorDelday, Margaret I
dc.contributor.authorEttorre, Anna
dc.contributor.authorMulder, Imke E
dc.date.accessioned2019-11-01T15:05:01Z
dc.date.available2019-11-01T15:05:01Z
dc.date.issued2019-09-20
dc.identifier.citationAhmed , S , Busetti , A , Fotiadou , P , Vincy Jose , N , Reid , S , Georgieva , M , Brown , S , Dunbar , H , Beurket-Ascencio , G , Delday , M I , Ettorre , A & Mulder , I E 2019 , ' In vitro Characterization of Gut Microbiota-Derived Bacterial Strains With Neuroprotective Properties ' , Frontiers in cellular neuroscience , vol. 13 , 402 . https://doi.org/10.3389/fncel.2019.00402en
dc.identifier.issn1662-5102
dc.identifier.otherPURE: 148963065
dc.identifier.otherPURE UUID: b1433f35-31a2-4b2f-bf7f-9bdecd97fcae
dc.identifier.otherPubMed: 31619962
dc.identifier.otherPubMedCentral: PMC6763572
dc.identifier.otherWOS: 000487307600001
dc.identifier.otherScopus: 85073003892
dc.identifier.urihttps://hdl.handle.net/2164/13208
dc.descriptionAcknowledgments The authors are grateful to Dr. Nicole Reichardt and the 4D Pharma Isolation Team for their technical assistance with bacterial culture. Funding This work was privately funded by 4D Pharma PLC. The authors of the study, who are employees of (or in the case of MID, are funded by) 4D Pharma Research Ltd., a wholly owned subsidiary of the funder, were responsible for the design and execution of the study, as well as the analysis of the results obtained. Author Contributions In vitro experiments: AE, SA, and AB designed the experiments; SA, PF, NV, MG, SB, GB-A, and MD performed the majority of the in vitro experiments; SR, HD, and AB validated, performed, and analyzed the microbiological-related data output; AE coordinated and managed the research project; AE, SA, PF, and AB analyzed the data. IM oversaw the overall research plan. AE wrote the manuscript with the assistance of SA and AB. All authors have read and commented on the manuscript and have approved the final version of the manuscript. Data Availability: 16S gene sequences for MRx0005 and MRx0029 are disclosed in International Patent Publication Nos. WO2018/229189 and WO2018/229216, respectively, filed by 4D Pharma Research Ltd. The data supporting the findings in this paper are available within the article and its Supplementary Information Files.en
dc.language.isoeng
dc.relation.ispartofFrontiers in cellular neuroscienceen
dc.rightsThis is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. https://creativecommons.org/licenses/by/4.0/en
dc.subjectgut microbiota-derived bacterial strainsen
dc.subjectmicrobiomeen
dc.subjectneurodegenerative diseasesen
dc.subjectneuroinflammationen
dc.subjectneuroprotectionen
dc.subjectoxidative stressen
dc.subjectgut-brain axisen
dc.subjectshort-chain fatty acidsen
dc.subjectcellsen
dc.subjectbrain axisen
dc.subjectinvolvementen
dc.subjectdisordersen
dc.subjectmodelen
dc.subjectgas-chromatographyen
dc.subjectdistasonisen
dc.subjectchain fatty-acidsen
dc.subjectstressen
dc.subjectParkinson's diseaseen
dc.subjectQH301 Biologyen
dc.subjectSupplementary data availableen
dc.subject.lccQH301en
dc.titleIn vitro Characterization of Gut Microbiota-Derived Bacterial Strains With Neuroprotective Propertiesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.3389/fncel.2019.00402
dc.identifier.urlhttps://www.frontiersin.org/articles/10.3389/fncel.2019.00402/full#S10en


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