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N-Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathway

dc.contributor.authorDalponte, Luca
dc.contributor.authorParajuli, Anirudra
dc.contributor.authorYounger, Ellen
dc.contributor.authorMattila, Antti
dc.contributor.authorJokela, Jouni
dc.contributor.authorWahlsten, Matti
dc.contributor.authorLeikoski, Niina
dc.contributor.authorSivonen, Kaarina
dc.contributor.authorJarmusch, Scott A.
dc.contributor.authorHoussen, Wael E.
dc.contributor.authorFewer, David P.
dc.date.accessioned2019-11-19T00:03:39Z
dc.date.available2019-11-19T00:03:39Z
dc.date.issued2018
dc.identifier.citationDalponte , L , Parajuli , A , Younger , E , Mattila , A , Jokela , J , Wahlsten , M , Leikoski , N , Sivonen , K , Jarmusch , S A , Houssen , W E & Fewer , D P 2018 , ' N-Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathway ' , Biochemistry , vol. 57 , no. 50 , pp. 6860-6867 . https://doi.org/10.1021/acs.biochem.8b00879en
dc.identifier.issn0006-2960
dc.identifier.otherPURE: 140768883
dc.identifier.otherPURE UUID: fb0070e2-6c89-4097-9b2b-8a62f54e0c12
dc.identifier.otherRIS: urn:46735832A3724B81D40E1D3CFEA2796B
dc.identifier.otherScopus: 85058084461
dc.identifier.urihttps://hdl.handle.net/2164/13280
dc.descriptionFunding This work was supported by grants from the Academy of Finland (259505, D.P.F.), Helsinki University Research grant (490085, D.P.F.) ESCMID grant (4720572, D.P.F.), the Industrial Biotechnology Innovation Centre (IBioIC) studentship (L. D.), the Jane and Aatos Erkko Foundation (K.S.), the BBSRC FoF grant (no BB/M013669/1, W. E. H.), IBCatalyst grant (no. BB/M028526/1, W. E. H.), the Sarcoma UK grant (W. E. H.) and the SULSA Leaders and SULSA PECRE awards (W. E. H.). W. E. H. acknowledges the fund from the ERC grant no. 339367. ACKNOWLEDGEMENTS D.P.F. and K.S. are grateful to Lyudmila Saari, Department of Microbiology, University of Helsinki, for her valuable help in handling the Anabaena sp. UHCC-0232 culture. W. E. H. thanks the Aberdeen Proteomics Facility and the Marine Biodiscovery Centre Mass Spectrometry Facility for extensive MS analysis. W. E. H. is grateful to Mr. Russell Gray (Marine Biodiscovery Centre, University of Aberdeen) for the NMR analysis of our samples.en
dc.format.extent8
dc.language.isoeng
dc.relation.ispartofBiochemistryen
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Biochemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://pubs.acs.org/doi/10.1021/acs.biochem.8b00879.en
dc.subjectAnacyclamidesen
dc.subjectAnabaenaen
dc.subjecttryptophan prenylationen
dc.subjectcyanobactinsen
dc.subjectABBA aromatic prenyltransferaseen
dc.subjectN-prenylationen
dc.subjectQD Chemistryen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/M013669/1en
dc.subjectEuropean Research Councilen
dc.subject339367en
dc.subject.lccQDen
dc.titleN-Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathwayen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Natural & Computing Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1021/acs.biochem.8b00879
dc.date.embargoedUntil2019-11-19


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