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dc.contributor.authorGibson, Jude
dc.contributor.authorRuss, Tom C.
dc.contributor.authorClarke, Toni-Kim
dc.contributor.authorHoward, David M.
dc.contributor.authorHillary, Robert F.
dc.contributor.authorEvans, Kathryn L.
dc.contributor.authorWalker, Rosie M.
dc.contributor.authorBermingham, Mairead L.
dc.contributor.authorMorris, Stewart W.
dc.contributor.authorCampbell, Archie
dc.contributor.authorHayward, Caroline
dc.contributor.authorMurray, Alison D.
dc.contributor.authorPorteous, David J.
dc.contributor.authorHorvath, Steve
dc.contributor.authorLu, Ake T.
dc.contributor.authorMcIntosh, Andrew M.
dc.contributor.authorWhalley, Heather C.
dc.contributor.authorMarioni, Riccardo E.
dc.date.accessioned2019-12-24T13:20:01Z
dc.date.available2019-12-24T13:20:01Z
dc.date.issued2019-11
dc.identifier.citationGibson , J , Russ , T C , Clarke , T-K , Howard , D M , Hillary , R F , Evans , K L , Walker , R M , Bermingham , M L , Morris , S W , Campbell , A , Hayward , C , Murray , A D , Porteous , D J , Horvath , S , Lu , A T , McIntosh , A M , Whalley , H C & Marioni , R E 2019 , ' A meta-analysis of genome-wide association studies of epigenetic age acceleration ' , PLoS Genetics , vol. 15 , no. 11 , e1008104 . https://doi.org/10.1371/journal.pgen.1008104en
dc.identifier.issn1553-7390
dc.identifier.otherPURE: 149169969
dc.identifier.otherPURE UUID: 4db26fb5-6362-4e80-8eac-31ca3ad17bec
dc.identifier.otherRIS: urn:3E5F225DAD962F99F578B949919F6817
dc.identifier.otherRIS: urn:3E5F225DAD962F99F578B949919F6817
dc.identifier.otherPubMed: 31738745
dc.identifier.otherScopus: 85076045038
dc.identifier.otherORCID: /0000-0003-4915-4847/work/76976595
dc.identifier.urihttps://hdl.handle.net/2164/13427
dc.descriptionFunding: Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006). Genotyping and DNA methylation profiling of the GS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” ((STRADL) Reference 104036/Z/14/Z)). Funding details for the cohorts included in the study by Lu et al. (2018) can be found in their publication. HCW is supported by a JMAS SIM fellowship from the Royal College of Physicians of Edinburgh and by an ESAT College Fellowship from the University of Edinburgh. AMM & HCW acknowledge the support of the Dr. Mortimer and Theresa Sackler Foundation. SH acknowledges support from grant 1U01AG060908-01. REM is supported by Alzheimer’s Research UK major project grant ARUK-PG2017B-10. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Data Availability: Summary statistics from the research reported in the manuscript will be made available immediately following publication on the Edinburgh Data Share portal with a permanent digital object identifier (DOI). According to the terms of consent for Generation Scotland participants, requests for access to the individual-level data must be reviewed by the GS Access Committee (resources@generationscotland.org). Individual-level data are not immediately available, due to confidentiality considerations and our legal obligation to protect personal information. These data will, however, be made available upon request and after review by the GS access committee, once ethical and data governance concerns regarding personal data have been addressed by the receiving institution through a Data Transfer Agreement.en
dc.format.extent30
dc.language.isoeng
dc.relation.ispartofPLoS Geneticsen
dc.rightsCopyright: © 2019 Gibson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. https://creativecommons.org/licenses/by/4.0/en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectDNA methylationen
dc.subjectageingen
dc.subjectsexual dimorphismen
dc.subjectX-chromosomeen
dc.subjectGeneration Scotlanden
dc.subjectQH426 Geneticsen
dc.subjectR Medicineen
dc.subjectGenetics(clinical)en
dc.subjectGeneticsen
dc.subjectEcology, Evolution, Behavior and Systematicsen
dc.subjectMolecular Biologyen
dc.subjectCancer Researchen
dc.subjectSupplementary Dataen
dc.subject.lccQH426en
dc.subject.lccRen
dc.titleA meta-analysis of genome-wide association studies of epigenetic age accelerationen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Data Safe Havenen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1371/journal.pgen.1008104
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85076045038&partnerID=8YFLogxKen


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