Show simple item record

dc.contributor.authorHumphries, Matthew P.
dc.contributor.authorCraig, Stephanie G.
dc.contributor.authorKacprzyk, Rafal
dc.contributor.authorFisher, Natalie C.
dc.contributor.authorBingham, Victoria
dc.contributor.authorMcQuaid, Stephen
dc.contributor.authorMurray, Graeme I.
dc.contributor.authorMcManus, Damian
dc.contributor.authorTurkington, Richard C.
dc.contributor.authorJames, Jacqueline
dc.contributor.authorSalto-Tellez, Manuel
dc.date.accessioned2020-06-03T09:15:01Z
dc.date.available2020-06-03T09:15:01Z
dc.date.issued2020-06-01
dc.identifier.citationHumphries , M P , Craig , S G , Kacprzyk , R , Fisher , N C , Bingham , V , McQuaid , S , Murray , G I , McManus , D , Turkington , R C , James , J & Salto-Tellez , M 2020 , ' The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation ' , BMC Cancer , vol. 20 , 500 . https://doi.org/10.1186/s12885-020-06987-yen
dc.identifier.issn1471-2407
dc.identifier.otherPURE: 170338206
dc.identifier.otherPURE UUID: 52c8c039-8912-4066-b667-100b1ebee248
dc.identifier.otherScopus: 85085910113
dc.identifier.otherWOS: 000538120900001
dc.identifier.otherPubMed: 32487090
dc.identifier.otherORCID: /0000-0003-3981-2420/work/76973683
dc.identifier.urihttps://hdl.handle.net/2164/14430
dc.descriptionAcknowledgments The samples used in this research were received from the Northern Ireland Biobank, which has ethical approval to use de-identified tissue samples from the Belfast Health and Social Care Tissue Pathology archive (REC:11/NI/0013). The Northern Ireland Molecular Pathology Laboratory, was responsible for construction of tissue microarrays, slide staining, and scanning. We are grateful to the NVIDIA Corporation for supporting our research via the GPU Grant Program for researchers. The research leading to these results has also received funding from Invest Northern Ireland. The authors thank Mr. Ken Arthur for the construction of the original tissue microarrays used in this study. Funding This study was funded by a CRUK Accelerator Grant (A20256) to JJ and MST. CRUK had no role in the study design, collection, analysis, and interpretation of the data or in the writing of the report.en
dc.format.extent11
dc.language.isoeng
dc.relation.ispartofBMC Canceren
dc.rights© The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectEsophageal adenocarcinomaen
dc.subjectImmune checkpointen
dc.subjectMultiplex IHCen
dc.subjectImage analysisen
dc.subjectBIOMARKERSen
dc.subjectSURVIVALen
dc.subjectPROGRAMMED DEATH-1en
dc.subjectPROGNOSTIC-SIGNIFICANCEen
dc.subjectLARGE COHORTen
dc.subjectCANCERen
dc.subjectLIGAND 1 EXPRESSIONen
dc.subjectR Medicine (General)en
dc.subjectGeneticsen
dc.subjectOncologyen
dc.subjectCancer Researchen
dc.subjectCancer Research UKen
dc.subjectA20256en
dc.subjectSupplementary Dataen
dc.subject.lccR1en
dc.titleThe adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitationen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1186/s12885-020-06987-y
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85085910113&partnerID=8YFLogxKen


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record