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dc.contributor.authorGonçalves, Samuel M.
dc.contributor.authorDuarte-Oliveira, Cláudio
dc.contributor.authorCampos, Cláudia F.
dc.contributor.authorAimanianda, Vishukumar
dc.contributor.authorter Horst, Rob
dc.contributor.authorLeite, Luis
dc.contributor.authorMercier, Toine
dc.contributor.authorPereira, Paulo
dc.contributor.authorFernández-García, Miguel
dc.contributor.authorAntunes, Daniela
dc.contributor.authorRodrigues, Cláudia S.
dc.contributor.authorBarbosa-Matos, Catarina
dc.contributor.authorGaifem, Joana
dc.contributor.authorMesquita, Inês
dc.contributor.authorMarques, António
dc.contributor.authorOsório, Nuno S.
dc.contributor.authorTorrado, Egídio
dc.contributor.authorRodrigues, Fernando
dc.contributor.authorCosta, Sandra
dc.contributor.authorJoosten, Leo A.B.
dc.contributor.authorLagrou, Katrien
dc.contributor.authorMaertens, Johan
dc.contributor.authorLacerda, João F
dc.contributor.authorCampos Jr, António
dc.contributor.authorBrown, Gordon D.
dc.contributor.authorBrakhage, Axel A
dc.contributor.authorBarbas, Coral
dc.contributor.authorSilvestre, Ricardo
dc.contributor.authorvan de Veerdonk, Frank L.
dc.contributor.authorChamilos, Georgios
dc.contributor.authorNetea, Mihai G.
dc.contributor.authorLatgé, Jean-Paul
dc.contributor.authorCunha, Cristina
dc.contributor.authorCarvalho, Agostinho
dc.date.accessioned2020-06-15T18:05:01Z
dc.date.available2020-06-15T18:05:01Z
dc.date.issued2020
dc.identifier.citationGonçalves , S M , Duarte-Oliveira , C , Campos , C F , Aimanianda , V , ter Horst , R , Leite , L , Mercier , T , Pereira , P , Fernández-García , M , Antunes , D , Rodrigues , C S , Barbosa-Matos , C , Gaifem , J , Mesquita , I , Marques , A , Osório , N S , Torrado , E , Rodrigues , F , Costa , S , Joosten , L A B , Lagrou , K , Maertens , J , Lacerda , J F , Campos Jr , A , Brown , G D , Brakhage , A A , Barbas , C , Silvestre , R , van de Veerdonk , F L , Chamilos , G , Netea , M G , Latgé , J-P , Cunha , C & Carvalho , A 2020 , ' Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity ' , Nature Communications , vol. 11 , 2282 . https://doi.org/10.1038/s41467-020-16120-zen
dc.identifier.issn2041-1723
dc.identifier.otherPURE: 160372265
dc.identifier.otherPURE UUID: 1cba4992-2def-42ba-a1b8-45ab8c5e3412
dc.identifier.otherPubMed: 32385235
dc.identifier.otherPubMedCentral: PMC7210971
dc.identifier.otherScopus: 85084721395
dc.identifier.otherWOS: 000533936800006
dc.identifier.urihttps://hdl.handle.net/2164/14501
dc.descriptionAcknowledgements This work was supported by the Northern Portugal Regional Operational Programme (NORTE 2020), under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (FEDER) (NORTE-01- 0145-FEDER-000013), the Fundação para a Ciência e Tecnologia (FCT) (SFRH/BD/136814/2018 to S.M.G., SFRH/BD/141127/2018 to C.D.O., PD/BD/137680/2018 to D.A., IF/00474/2014 to N.S.O., IF/01390/2014 to E.T., IF/00959/2014 to S.C., IF/00021/2014 to R.S., PTDC/SAU-SER/29635/2017 and CEECIND/04601/2017 to C.C., and CEECIND/03628/2017 to A.C.), the Institut Mérieux (Mérieux Research Grant 2017 to C.C.), and the European Society of Clinical Microbiology and Infectious Diseases (ESCMID Research Grant 2017 to A.C.). M.G.N. was supported by a Spinoza grant of the Netherlands Organization for Scientific Research. A.A.B. was supported by the Deutsche Forschungsgemeinschaft Collaborative Research Center/Transregio TR124 FungiNet (project A1). G.D.B. was funded by the Wellcome Trust (102705), the MRC Centre for Medical Mycology and the University of Aberdeen (MR/N006364/1).en
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.rightsOpen Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.en
dc.subjectAspergillusen
dc.subjectmelaninen
dc.subjectimmunometabolismen
dc.subjectglycolysisen
dc.subjectcalciumen
dc.subjectmacrophageen
dc.subjectantifungal immunityen
dc.subjectinvasive pulmonary aspergillosisen
dc.subjectACTIVATIONen
dc.subjectASPERGILLUS-FUMIGATUSen
dc.subjectPHAGOCYTOSISen
dc.subjectDENDRITIC CELLen
dc.subjectCONIDIAen
dc.subjectMTORen
dc.subjectSUCCINATE-DEHYDROGENASEen
dc.subjectINHIBITIONen
dc.subjectBIOSYNTHESISen
dc.subjectCELLULAR-METABOLISMen
dc.subjectR Medicine (General)en
dc.subjectPhysics and Astronomy(all)en
dc.subjectChemistry(all)en
dc.subjectBiochemistry, Genetics and Molecular Biology(all)en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/N006364/1en
dc.subjectWellcome Trusten
dc.subject102705en
dc.subjectSupplementary data availableen
dc.subject.lccR1en
dc.titlePhagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunityen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1038/s41467-020-16120-z
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85084721395&partnerID=8YFLogxKen


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