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Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum

dc.contributor.authorEdwards, Catriona H
dc.contributor.authorChristie, Craig
dc.contributor.authorMasotti, Andrea
dc.contributor.authorCelluzzi, Antonella
dc.contributor.authorCaporali, Andrea
dc.contributor.authorCampbell, Ewan M
dc.date.accessioned2020-08-03T11:05:01Z
dc.date.available2020-08-03T11:05:01Z
dc.date.issued2020-07-24
dc.identifier.citationEdwards , C H , Christie , C , Masotti , A , Celluzzi , A , Caporali , A & Campbell , E M 2020 , ' Dendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneum ' , Scientific Reports , vol. 10 , 12422 . https://doi.org/10.1038/s41598-020-69068-xen
dc.identifier.issn2045-2322
dc.identifier.otherPURE: 171438361
dc.identifier.otherPURE UUID: 47d91526-3acc-4283-bf04-043fa6554a3f
dc.identifier.otherScopus: 85088386912
dc.identifier.otherPubMed: 32709999
dc.identifier.otherWOS: 000555461100006
dc.identifier.urihttps://hdl.handle.net/2164/14840
dc.descriptionThanks to Dr Alan S. Bowman at the Institute for Biological and Environmental Sciences, University of Aberdeen for providing facilities and laboratory equipment for insect work and to Kevin S. Mackenzie and staff at the Microscopy and Histology Core Facility at the University of Aberdeen for TEM preparations. Scottish Crucible Project Award 2014 provided financial support for this research. CHE was supported by a Knowledge Transfer Network BBSRC Industrial Case (BB/L502467/1) studentship. CRC was supported by a KTN BBSRC CASE studentship (BB/M503526/1). AM and AC were supported by the Italian Ministry of Health (RF-PE-2011-02347026). EMC was supported by European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no. 613960 (SMARTBEES) and Veterinary Medicines Directorate, Department for Environment Food & Rural Affairs (Project # VM0517).en
dc.format.extent11
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.rightsThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.en
dc.subjectanimal physiologyen
dc.subjectnanobiotechnologyen
dc.subjectRNAien
dc.subjectCELLSen
dc.subjectNANOMATERIALSen
dc.subjectTOXICITYen
dc.subjectMECHANISMSen
dc.subjectAEDES-AEGYPTIen
dc.subjectLARVALen
dc.subjectNANOPARTICLESen
dc.subjectRNA INTERFERENCE KNOCKDOWNen
dc.subjectDEGRADATIONen
dc.subjectORAL RNAIen
dc.subjectQH301 Biologyen
dc.subjectGeneralen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/L502467/1en
dc.subjectBB/M503526/1en
dc.subject.lccQH301en
dc.titleDendrimer-coated carbon nanotubes deliver dsRNA and increase the efficacy of gene knockdown in the red flour beetle Tribolium castaneumen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1038/s41598-020-69068-x
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85088386912&partnerID=8YFLogxKen
dc.identifier.vol10en


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