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Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes

dc.contributor.authorKolb, Andreas F.
dc.contributor.authorPetrie, Linda
dc.contributor.authorMayer, Claus D.
dc.contributor.authorPirie, Lynn
dc.contributor.authorDuthie, Susan J.
dc.date.accessioned2020-09-16T23:03:27Z
dc.date.available2020-09-16T23:03:27Z
dc.date.issued2019
dc.identifier.citationKolb , A F , Petrie , L , Mayer , C D , Pirie , L & Duthie , S J 2019 , ' Folate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genes ' , Biochemical Journal , vol. 476 , no. 19 , pp. 2769-2795 . https://doi.org/10.1042/BCJ20190275en
dc.identifier.issn0264-6021
dc.identifier.otherPURE: 148063152
dc.identifier.otherPURE UUID: fcbf7808-24e6-44b5-8ec0-2f0cba4d2293
dc.identifier.otherRIS: urn:6840E0668CB39BD575CAE1277914A18B
dc.identifier.otherPubMed: 31530711
dc.identifier.otherWOS: 000489732900006
dc.identifier.otherScopus: 85074184742
dc.identifier.otherORCID: /0000-0001-9056-5504/work/81608884
dc.identifier.urihttps://hdl.handle.net/2164/15140
dc.descriptionAcknowledgements Microarray data shown in this manuscript have been deposited at NCBI via the Gene Expression Omnibus webpage under number: GSE125502. This work was funded by The Scottish Government Rural and Environment Science and Analytical Services Division (RESAS). The funder had no role in the design of the study, the analysis and interpretation of the data, or the publication process. The authors would like to thank Drs Bill Rees and Perry Barrett for helpful discussions throughout the project and on the manuscript. There are no competing interests to declare.en
dc.format.extent7
dc.language.isoeng
dc.relation.ispartofBiochemical Journalen
dc.rights©2019 The Author(s) This is an Accepted Manuscript; not the final Version of Record. Archiving permitted only in line with the archiving policy of Portland Press Limited. All other rights reserved.en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectB-vitaminsen
dc.subjectfolateen
dc.subjectvascular smooth muscle cellsen
dc.subjectDNA methylationen
dc.subjectgene regulationen
dc.subjectFOLIC-ACID FORTIFICATIONen
dc.subjectHYPERHOMOCYSTEINEMIAen
dc.subjectVITAMINS-Ben
dc.subjectDNA METHYLATIONen
dc.subjectMICE DEFICIENTen
dc.subjectATHEROSCLEROSISen
dc.subjectSUPPLEMENTATIONen
dc.subjectNUTRITIONen
dc.subjectEXPRESSIONen
dc.subjectPLASMA HOMOCYSTEINEen
dc.subjectR Medicine (General)en
dc.subjectMolecular Biologyen
dc.subjectBiochemistryen
dc.subjectCell Biologyen
dc.subjectRural and Environmental Science and Analytical Services (RESAS)en
dc.subject.lccR1en
dc.titleFolate deficiency promotes differentiation of vascular smooth muscle cells without affecting the methylation status of regulated genesen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.description.statusPeer revieweden
dc.description.versionPostprinten
dc.identifier.doihttps://doi.org/10.1042/BCJ20190275
dc.date.embargoedUntil2020-09-17
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85074184742&partnerID=8YFLogxKen
dc.identifier.vol476en
dc.identifier.iss19en


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