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dc.contributor.authorLuna-Viramontes, Nabil Itzi
dc.contributor.authorCampa-Córdoba, B. Berenice
dc.contributor.authorOntiveros-Torres, Miguel Angel
dc.contributor.authorHarrington, Charles R
dc.contributor.authorVillanueva-Fierro, Ignacio
dc.contributor.authorGuadarrama-Ortíz, Parménides
dc.contributor.authorGarcés-Ramírez, Linda
dc.contributor.authorde la Cruz, Fidel
dc.contributor.authorHernandes-Alejandro, Mario
dc.contributor.authorMartínez-Robles, Sandra
dc.contributor.authorGonzález-Ballesteros, Erik
dc.contributor.authorPacheco-Herrero, Mar
dc.contributor.authorLuna-Muñoz, José
dc.date.accessioned2020-10-23T09:02:01Z
dc.date.available2020-10-23T09:02:01Z
dc.date.issued2020-09-10
dc.identifier.citationLuna-Viramontes , N I , Campa-Córdoba , B B , Ontiveros-Torres , M A , Harrington , C R , Villanueva-Fierro , I , Guadarrama-Ortíz , P , Garcés-Ramírez , L , de la Cruz , F , Hernandes-Alejandro , M , Martínez-Robles , S , González-Ballesteros , E , Pacheco-Herrero , M & Luna-Muñoz , J 2020 , ' PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Disease ' , Frontiers in cellular neuroscience , vol. 14 , 247 . https://doi.org/10.3389/fncel.2020.00247en
dc.identifier.issn1662-5102
dc.identifier.otherPURE: 178304792
dc.identifier.otherPURE UUID: aeee75f6-60fa-43af-9881-b1709a28c2ae
dc.identifier.otherScopus: 85091531587
dc.identifier.otherPubMed: 33132840
dc.identifier.urihttps://hdl.handle.net/2164/15277
dc.descriptionFUNDING This work was supported by Fondo Nacional de Ciencia, Tecnologia, FONDOCyT, from the Ministry of Higher Education, Science and Technology, Dominican Republic (2015- 3A2-127 to MP-H and 2018-2019-2A3-208 to JL-M and MP-H). ACKNOWLEDGMENTS: We want to express our gratitude to the following: Dr. P. Davies (Albert Einstein College of Medicine, Bronx, NY, United States) and Lester I. Binder† (North Western, Chicago, IL, United States) for the generous gifts of mAbs TG3 and Alz-50, and Tau-1, Tau-5, and Tau-7, respectively; Tec. Amparo Viramontes Pintos for the handling of the brain tissue; Samadhi Moreno-Campuzano for her technical assistance/support in the confocal microscopy unit of CIIDIR Durango, Instituto Politécnico Nacional; Union Medical University Clinic, Dominican Republic, for their support and collaboration in the development of this research project. We also want to express our gratitude to the Mexican families who have donated the brain of their loved ones affected with Alzheimer’s disease and made our research possible. This work is dedicated to the memory of Professor Dr. José Raúl Mena López† .en
dc.format.extent11
dc.language.isoeng
dc.relation.ispartofFrontiers in cellular neuroscienceen
dc.rightsCopyright © 2020 Luna-Viramontes, Campa-Córdoba, Ontiveros-Torres, Harrington, Villanueva-Fierro, Guadarrama-Ortíz, Garcés-Ramírez, de la Cruz, Hernandes-Alejandro, Martínez-Robles, González-Ballesteros, Pacheco-Herrero and Luna-Muñoz. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. https://creativecommons.org/licenses/by/4.0/en
dc.subjecttau proteinen
dc.subjecttau pathologyen
dc.subjectPHF coreen
dc.subjectTruncationen
dc.subjectphosphorylationen
dc.subjectconformational changesen
dc.subjectpaired helical filamenten
dc.subjectneurofibrillary tanglesen
dc.subjecttruncationen
dc.subjectR Medicineen
dc.subjectCellular and Molecular Neuroscienceen
dc.subject.lccRen
dc.titlePHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Diseaseen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Clinical Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.3389/fncel.2020.00247
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85091531587&partnerID=8YFLogxKen


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