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Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia

dc.contributor.authorLemke, Nora
dc.contributor.authorMelis, Valeria
dc.contributor.authorLauer, Dilyara
dc.contributor.authorMagbagbeolu, Mandy
dc.contributor.authorNeumann, Boris
dc.contributor.authorHarrington, Charles R
dc.contributor.authorRiedel, Gernot
dc.contributor.authorWischik, Claude M.
dc.contributor.authorTheuring, Franz
dc.contributor.authorSchwab, Karima
dc.date.accessioned2020-11-03T09:41:01Z
dc.date.available2020-11-03T09:41:01Z
dc.date.issued2020-12-25
dc.identifier.citationLemke , N , Melis , V , Lauer , D , Magbagbeolu , M , Neumann , B , Harrington , C R , Riedel , G , Wischik , C M , Theuring , F & Schwab , K 2020 , ' Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia ' , Journal of Biological Chemistry , vol. 295 , no. 52 , pp. 18508-18523 . https://doi.org/10.1074/jbc.RA120.014890en
dc.identifier.issn0021-9258
dc.identifier.otherPURE: 178981139
dc.identifier.otherPURE UUID: 807fd2c7-7dbe-4a0f-9503-10fdff1e89d9
dc.identifier.otherBibtex: Lemke30102020
dc.identifier.otherPubMed: 33127647
dc.identifier.otherScopus: 85098333503
dc.identifier.otherPubMed: 33453851
dc.identifier.otherORCID: 0000-0003-2250-3920
dc.identifier.otherORCID: 0000-0001-7063-7136
dc.identifier.otherORCID: /0000-0001-7063-7136/work/96652484
dc.identifier.otherWOS: 000603645900047
dc.identifier.urihttps://hdl.handle.net/2164/15308
dc.descriptionFunding Information: Funding and additional information—This work was supported by EMPIR programme in Research Project 15HLT02 ReMiND cofinanced by the Participating States and the European Union's Horizon 2020 research and innovation programme (to N. L.). Work was also supported by WisTa Laboratories Ltd. (to V. M., D. L., M. M., C. R. H., G. R., C. M. W., F. T., and K. S.). Conflict of interest—This work was sponsored by WisTa Laboratories Ltd., an affiliate of TauRx Therapeutics Ltd. C. R. H. and C. M. W. are employees and officers of TauRx Therapeutics Ltd.en
dc.format.extent16
dc.language.isoeng
dc.relation.ispartofJournal of Biological Chemistryen
dc.rightsAuthor's Choice—Final version open access under the terms of the Creative Commons CC-BY license.https://creativecommons.org/licenses/by/4.0/en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectQD Chemistryen
dc.subjectMolecular Biologyen
dc.subjectBiochemistryen
dc.subjectCell Biologyen
dc.subjectOtheren
dc.subjectSupplementary Dataen
dc.subject.lccQDen
dc.titleDifferential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementiaen
dc.typeJournal articleen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.description.statusPeer revieweden
dc.description.versionPublisher PDFen
dc.identifier.doihttps://doi.org/10.1074/jbc.RA120.014890
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85098333503&partnerID=8YFLogxKen
dc.identifier.urlhttps://massive.ucsd.edu/ProteoSAFe/static/massive.jspen
dc.identifier.urlhttp://www.jbc.org/content/early/2020/10/30/jbc.RA120.014890.abstracten
dc.identifier.vol295en
dc.identifier.iss52en


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